Coagulation Factor XIII, A1 Polypeptide Proteins (F13A1)

F13A1 encodes the coagulation factor XIII A subunit.

list all proteins Gene Name GeneID UniProt
Rat F13A1 F13A1 60327 O08619
Human F13A1 F13A1 2162 P00488
Mouse F13A1 F13A1 74145 Q8BH61
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Top Coagulation Factor XIII, A1 Polypeptide Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$656.00
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Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$688.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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Human Human His tag   10 μg Log in to see 15 to 16 Days
$250.00
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Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,361.33
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Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$4,020.50
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Human Human Un-conjugated 1 mg Log in to see 2 to 3 Days
$1,177.00
Details

More Proteins for Coagulation Factor XIII, A1 Polypeptide (F13A1) Interaction Partners

Cow (Bovine) Coagulation Factor XIII, A1 Polypeptide (F13A1) interaction partners

  1. kinetic and structural analysis of interactions between thrombin (show F2 Proteins) and the Factor XIII (show UGDH Proteins) activation peptide

Human Coagulation Factor XIII, A1 Polypeptide (F13A1) interaction partners

  1. Our meta-analysis supports an association between F13A1 Val34Leu and recurrent pregnancy loss.

  2. A brief history of some key events in the conversion of fibrinogen to fibrin has been reviewed. (Review)

  3. The results of this study suggest that these biomarker F13A1 can serve as a potential non-invasive early diagnosis platform reflecting PiB-PET imaging for Mild Cognitive Impairment and Alzheimer's Disease.

  4. F13A1 gene mutations in 73 patients treated with recombinant FXIII-A2

  5. These findings provide insight into assembly of the fibrinogen/FXIII-A2B2 complex in both physiologic and therapeutic situations.

  6. FXIIIa exhibits a preference for Q237 in crosslinking reactions within fibrinogen alphaC (233-425) followed by Q328 and Q366.

  7. factor XIII (show UGDH Proteins) Val34Leu polymorphism is associated with coronary artery diseases risk, especially myocardial infarction. Age and sex did not affect the relationship between factor XIII (show UGDH Proteins) Val34Leu polymorphism and diseases risk (Meta-Analysis)

  8. Genetic basis of severe factor XIII (show UGDH Proteins) deficiency in a large cohort of Indian patients has been uncovered.

  9. Mutations in the activation peptide of full-length recombinant FXIII regulate activation rates by thrombin (show F2 Proteins), and V34L influences in vivo thrombus formation by increased cross-linking of the clot (show TXNDC17 Proteins).

  10. Report immunochromatographic test for detection of anti-factor XIII (show UGDH Proteins) A subunit antibodies that can diagnose 90 % of cases with autoimmune haemorrhaphilia XIII (show UGDH Proteins).

Mouse (Murine) Coagulation Factor XIII, A1 Polypeptide (F13A1) interaction partners

  1. Factor XIII (show UGDH Proteins)-A and TG2 (show TGM2 Proteins) regulate resorption, adipogenesis and plasma fibronectin (show FN1 Proteins) homeostasis in bone and bone marrow.

  2. These findings provide insight into assembly of the fibrinogen/FXIII-A2B2 complex in both physiologic and therapeutic situations.

  3. Mast cells have the ability to produce and degrade FXIIIA depending on their chymase (show CMA1 Proteins) expression profile: mast cells expressing chymase (show CMA1 Proteins) degrade FXIIIA, whereas mast cells that do not express chymase (show CMA1 Proteins) mainly produce FXIIIA

  4. A lack of factor XIII (show UGDH Proteins) leads to prolonged clotting times, increased signs of inflammation, and elevated bacterial dissemination in streptococcal skin diseases.

  5. These findings expose a newly recognized, essential role for fibrin crosslinking during whole blood clot (show TXNDC17 Proteins) formation and consolidation and establish FXIIIa activity as a key determinant of thrombus composition and size.

  6. 5-HT (show DDC Proteins) inhibits Factor XIII (show UGDH Proteins)-A-mediated plasma fibronectin (show FN1 Proteins) matrix assembly and crosslinking in osteoblast cultures via direct competition with transamidation

  7. High Transglutaminase factor XIII (show UGDH Proteins) promotes arthritis through mechanisms linked to inflammation and bone erosion.

  8. Fibrinogen from mice harboring the Fibgamma390-396A mutation exhibited reduced binding to FXIII, and plasma from these mice exhibited delayed FXIII activation and fibrin crosslinking, indicating these residues mediate FXIII binding and activation.

  9. FXIII-A serves as a preadipocyte-bound proliferation/differentiation switch that mediates effects of hepatocyte-produced circulating pFN.

  10. Physiological significance of mouse TG2 (show TGM2 Proteins) and Factor XIII (show UGDH Proteins) through identification of substrate proteins in MC3T3-E1 cells.

Coagulation Factor XIII, A1 Polypeptide (F13A1) Protein Profile

Protein Summary

This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits\; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.

Gene names and symbols associated with F13A1

  • coagulation factor XIII A1 chain (F13a1)
  • coagulation factor XIII, A1 polypeptide b (f13a1b)
  • coagulation factor XIII A chain (F13A1)
  • coagulation factor XIII, A1 subunit (F13a1)
  • coagulation factor XIII A chain (F13a1)
  • 1200014I03Rik protein
  • AI462306 protein
  • F13A protein
  • F13A1 protein
  • wu:fo83d04 protein
  • zgc:153334 protein

Protein level used designations for F13A1

coagulation factor XIII A chain , coagulation factor XIII, A1 subunit , coagulation factor XIIIa , protein-glutamine gamma-glutamyltransferase A chain , transglutaminase A chain , FX111a-87 , fo83d04 , coagulation factor XIII A1 subunit , coagulation factor XIII, A1 polypeptide , blood coagulation factor XIII A1 subunit , coagulation factor XIIIA , Coagulation factor XIII A chain , FSF, A subunit , TGase , bA525O21.1 (coagulation factor XIII, A1 polypeptide) , coagulation factor XIII, A polypeptide , factor XIIIa , fibrin stabilizing factor, A subunit , fibrinoligase , transglutaminase. plasma , Factor XIIIA , coagulation factor XIII, alpha subunit , coagulation factor XIII A chain-like

GENE ID SPECIES
60327 Rattus norvegicus
561287 Danio rerio
478711 Canis lupus familiaris
462413 Pan troglodytes
100060428 Equus caballus
617881 Bos taurus
395420 Gallus gallus
711264 Macaca mulatta
2162 Homo sapiens
74145 Mus musculus
100020636 Monodelphis domestica
100401849 Callithrix jacchus
100479900 Ailuropoda melanoleuca
100539806 Meleagris gallopavo
100581513 Nomascus leucogenys
100153504 Sus scrofa
100719684 Cavia porcellus
101108612 Ovis aries
101671512 Mustela putorius furo
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