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CDKL1 product is a member of a large family of CDC2-related serine/threonine protein kinases. Additionally we are shipping CDKL1 Proteins (6) and CDKL1 Kits (1) and many more products for this protein.
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Chk1 directly interacts with MYPT1 and preferentially phosphorylates MYPT1 at Ser20, which is essential for MYPT1-PP1cbeta interaction and subsequent Plk1 dephosphorylation.
CDKL1 overexpression decreased the chemosensitivity of oral squamous cell carcinoma cells to hydroxycamptothecin.
CDKL1 plays an important role in neuroblastoma cell proliferation, migration and invasion.
CDKL1 was overexpressed in breast cancer patients and had a positive detection efficiency of 77% (144/186).
High expression of CDKL1 protein was associated with gastric cancer.
This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the nucleus. Alternative splice variants encoding different protein isoforms have been described, but their full-length nature has not been determined.
cyclin-dependent kinase-like 1 (CDC2-related kinase)
, CDC2-related kinase 1
, cyclin-dependent kinase-like 1
, protein kinase p42 KKIALRE
, serine/threonine protein kinase KKIALRE
, serine/threonine-protein kinase KKIALRE