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DMGDH encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. Additionally we are shipping DMGDH Antibodies (38) and DMGDH Kits (7) and many more products for this protein.
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In nonalcoholic fatty liver disease patient, the missense variant p.Ser646Pro (rs1805074) in DMGDH gene was significantly associated with disease severity and circulating levels of dimethylglycine.
The structure-based analysis provided new insights into the kinetic properties of dimethylglycine dehydrogenase in particular with respect to oxygen reactivity.
In agreement with previous studies, we show that the genetic variant rs921943 in DMGDH is significantly associated with selenium status in United Kingdom pregnant women.
Genetic variation of DMGDH was associated with higher plasma insulin (show INS Proteins), increased insulin (show INS Proteins) resistance and increased risk of incident diabetes.
analysis of dimethylglycine dehydrogenase deficiency associated with pathogenic variant H109R
ARC may protect cardiomyocytes from hypoxic cell death by regulating its downstream, Drbp1 and pMe(2)GlyDH
This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum.
, dimethylglycine dehydrogenase, mitochondrial
, dimethylglycine dehydrogenase, mitochondrial-like
, Dimethylglycine dehydrogenase