anti-G Protein-Coupled Receptor 183 (GPR183) Antibodies

GPR183 was identified by the up-regulation of its expression upon Epstein-Barr virus infection of primary B lymphocytes. Additionally we are shipping GPR183 Proteins (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GPR183 1880 P32249
GPR183 321019 Q3U6B2
GPR183 679975  
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Top anti-GPR183 Antibodies at antibodies-online.com

Showing 10 out of 44 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-GPR183 Antibody Titration: 1.0 ug/ml Positive Control: 293T Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 6 to 7 Days
$291.53
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-GPR183 / EBI2 antibody  ABIN1048772 IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-GPR183 / EBI2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Anti-GPR183 / EBI2 antibody IHC of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemistry-Paraffin: EBI2/GPR183 Antibody [NLS46] - Analysis of anti-GPR183 / EBI2 antibody with human lymph node at 4 ug/ ml. Immunohistochemistry: EBI2/GPR183 Antibody [NLS46] - Analysis of anti-GPR183 / EBI2 antibody with lymph node. 0.05 mL Log in to see 10 to 13 Days
$516.98
Details
Human Goat Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB 100 μg Log in to see 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated ELISA, IHC, WB ABIN6273906 at 1/100 staining Mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of EBI2 expression in A431 whole cell lysate ,The lane on the left is treated with the antigen-specific peptide. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of EBI2 expression in A431 whole cell lysate ,The lane on the left is treated with the antigen-specific peptide. 100 μL Log in to see 11 to 12 Days
$390.77
Details

More Antibodies against GPR183 Interaction Partners

Human G Protein-Coupled Receptor 183 (GPR183) interaction partners

  1. These data suggest a significant role for EBI2 in human CD4(+) T cell migration, notably in patients with multiple sclerosis.

  2. Studies provide evidence that EBI2 and oxysterols are important players not only in the immune system but also in the central nervous system. Proper functioning of the EBI2/oxysterol system seems crucial for healthy physiology and prevention of the onset or progression of several neurodegenerative diseases. [review]

  3. Human EBI2 (GPR183) expression in mice leads to an abnormally expanded CD5+ B1a B-cell subset and chronic lymphocytic leukemia-like B-cell malignancies.

  4. On ligand engagement, EBI2 typically signals via inhibitory G-protein subunit alpha to induce intracellular calcium mobilization, mitogen-activated protein kinase (MAPK) activation, and cell proliferation.

  5. this study concludes that EBI2 expression is directly influenced by EBV infection and that BRRF1 is necessary and sufficient for EBI2 upregulation during infection.

  6. These results demonstrate a role for EBI2 in astrocyte function and suggest that modulation of this receptor may be beneficial in neuroinflammatory disorders.

  7. EBI2 is expressed in primary human monocytes and macrophages.

  8. Chronic rhinosinusitis with nasal polyps is characterized by B-cell inflammation and EBV-induced protein 2 expression.

  9. This model of ligand docking yields important structural insight into the molecular mechanisms mediating EBI2 function.

  10. Data indicate that EBI2 expression modulates CXCL13 binding affinity to CXCR5.

  11. Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183).

  12. REVIEW: functional properties and in vivo biology

  13. Based on the constitutive signaling and cellular expression pattern of EBI2, it is suggested that it may function in conjunction with BILF1 in the reprogramming of the cell during EBV infection

  14. Structural motifs of importance for the constitutive activity of EBI2: analysis of receptor activation in the absence of an agonist.

Mouse (Murine) G Protein-Coupled Receptor 183 (GPR183) interaction partners

  1. This study support the hypothesis that EBI2/oxysterol signalling not only controls immune cell function, but may also adjust how astrocytes sense and respond to inflammatory stimuli

  2. GPR183 promotes lymphoid organ development and indicate that oxysterol-GPR183-dependent positioning within tissues controls group 3 innate lymphoid cells activity and intestinal homeostasis

  3. These results, for the first time, display a role for EBI2 in myelin development and protection from demyelination under pathophysiological conditions

  4. the data indicates that molecules in the EBI2 signalling pathway are sensitive to pro-inflammatory signals, and that EBI2 plays a role in communication between astrocytes and macrophages.

  5. EBI2 expressing cells are abundant within multiple sclerosis (MS) white matter lesions.

  6. These data identify a role for EBI2 in promoting efficient thymic central tolerance.

  7. mice lacking EBI2 in T cells or CD25 in dendritic cells have reduced T follicular helper cells and mount defective T-cell-dependent plasma cell and germinal centre responses

  8. findings establish an essential role for EBI2 in CD4(+) DC positioning and homeostasis and in facilitating capture and presentation of blood-borne particulate antigens

  9. EBI2 is a negative regulator of type I interferons in plasmacytoid and myeloid dendritic cells.

  10. Regulated expression of EBI2 on DC populations is therefore critical for the generation and correct positioning of splenic DCs and the initiation of immune responses.

  11. Regulation of B cell migration by EBI2 has an important role in controlling the positioning of activated B cells within lymphoid follicles in the early phases of B cell responses during cell differentiation and affinity maturation.

  12. These findings establish a role for EBI2 in helping control B cell position at multiple stages during the Ab response

  13. ligand targeting EBI2. In turn, this molecule provides a useful tool for further characterization of EBI2 as well as serving as a potent lead compound.

  14. important role for EBI2 in promoting B cell localization in the outer follicle, and show that differential expression of this receptor helps position B cells appropriately for mounting T-dependent antibody responses

  15. EBI2 provides a previously uncharacterized dimension to B cell migration that is crucial for coordinating rapid versus long-term antibody responses.

Zebrafish G Protein-Coupled Receptor 183 (GPR183) interaction partners

  1. Inhibition of Gpr183 significantly upregulates Notch signaling and abolishes embryonic hematopoietic stem and progenitor cells emergence.

GPR183 Antigen Profile

Protein Summary

This gene was identified by the up-regulation of its expression upon Epstein-Barr virus infection of primary B lymphocytes. This gene is predicted to encode a G protein-coupled receptor that is most closely related to the thrombin receptor. Expression of this gene was detected in B-lymphocyte cell lines and lymphoid tissues but not in T-lymphocyte cell lines or peripheral blood T lymphocytes. The function of this gene is unknown.

Gene names and symbols associated with GPR183

  • G protein-coupled receptor 183 (GPR183) antibody
  • G protein-coupled receptor 183 (Gpr183) antibody
  • G protein-coupled receptor 183a (gpr183a) antibody
  • ebi2 antibody
  • GPR183 antibody
  • gpr183a antibody
  • zgc:165579 antibody

Protein level used designations for GPR183

EBV-induced G-protein coupled receptor 2 , Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor) , G-protein coupled receptor 183 , epstein-Barr virus-induced G-protein coupled receptor 2 , EBV-induced G-protein coupled receptor 2 homolog , Epstein-Barr virus induced gene 2 , G protein-coupled receptor 183 , EBV-induced G protein-coupled receptor 2 , G-protein coupled receptor 183-A , G-protein coupled receptor 183-like

GENE ID SPECIES
1880 Homo sapiens
321019 Mus musculus
467308 Pan troglodytes
540287 Bos taurus
556770 Danio rerio
679975 Rattus norvegicus
698844 Macaca mulatta
100388743 Callithrix jacchus
100452504 Pongo abelii
106025223 Cavia porcellus
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