Hemoglobin, gamma A (HBG1) ELISA Kits

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Additionally we are shipping HBG1 Antibodies (49) and HBG1 Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat HBG1 HBG1 94164  
HBG1 3047 P69891
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Top HBG1 ELISA Kits at antibodies-online.com

Showing 3 out of 6 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 195.5 ng/mL 370.37 ng/mL - 30000 ng/mL 96 Tests 13 to 16 Days
Human 195.5 ng/mL 370.37 ng/mL - 30000 ng/mL   96 Tests 8 to 12 Days
Human < 195.5 ng/mL 370.37 ng/mL - 30000 ng/mL   96 Tests 11 to 18 Days

More ELISA Kits for HBG1 Interaction Partners

Human Hemoglobin, gamma A (HBG1) interaction partners

  1. This study explored BGLT3, an erythroid lncRNA encoded downstream of (A)gamma-globin (HBG1). BGLT3 and gamma-globin genes are dynamically cotranscribed in erythroid cells in vivo. Deletion of BGLT3 using CRISPR/Cas9 editing shows that it specifically contributes to regulation of gamma-globin genes.

  2. Some forms of hereditary persistence of fetal hemoglobin, a rare benign condition where individuals express the gamma-globin gene throughout adulthood, are caused by point mutations in the gamma-globin gene promoter at regions residing ~115 and 200 bp upstream of the transcription start site. We found that the major fetal globin gene repressors BCL11A and ZBTB7A directly bound to the sites at -115 and -200 bp, respecti...

  3. Data suggest that studying genotype frequency of the Xmn1 gammaG globin polymorphism (-158C>T ) in Siwa Oasis, Egypt can be considered as a starting point for further research targeting this community sector.

  4. A significant relationship between two variations (+25G/A and -499T/A) in Agamma gene promotor and fetal hemoglobin levels was observed.

  5. study describes the characterization of the rs368698783 (+25 G->A) polymorphism of the Agamma-globin gene associated in beta(0)39 thalassemia patients with high HbF in erythroid precursor cells

  6. Introduction of the British HPFH mutation into the fetal globin promoter in a human cell model causes elevated fetal globin expression. The British HPFH mutation creates a de novo binding site both in vitro and in vivo for the potent erythroid activator KLF1.

  7. A Ly1 antibody reactive (LYAR)-binding motif disruptive regulatory single-nucleotide polymorphisms rs368698783 (G/A) from LD block 5 in the proximal promoter of hemoglobin subunit gamma 1 (HBG1) was found to be a significant predictor for beta-thalassemia clinical severity.

  8. Study found a novel polymorphism of the A-gamma-globin gene in four families with b0-thalassemia and high levels of HbF expression. Additionally, evidence suggesting that the Ac-globin gene +25(G-A) polymorphism decreases the efficiency of the interaction between this sequence and specific DNA binding protein complexes.

  9. These data confirm the regulatory role of the HBG1: g.-225_-222 region that exerts its effect under conditions of erythropoietic stress characteristic for beta-thal patients.

  10. results suggest that KLF1 directly regulates the beta-globin gene, but probably has less direct impact on expression of the gamma-globin gene in fetal erythroblasts

  11. Data show that the ancestral allele C at rs2855126, located upstream of gamma-globin (HBG1) is associated with increased serum uric acid levels.

  12. analysis of a point mutation that increases fetal globin expression through de novo recruitment of the activator TAL1 to promote chromatin looping of distal enhancers to the modified gamma-globin promoter

  13. a successful induction of gamma-globin includes a reduction in BCL11A, KLF1 and TAL1 expression.

  14. This report we discusses the molecular characteristics and diagnostic criteria of a new (A)gamma chain variant that was detected during newborn screening and named Hb F-Sykesville MD [(A)gamma113(G15)Val --> Ile; HBG1: c.340G>A].

  15. Results indicate that compound II induces the gamma globin gene in hydroxyurea (HU)-resistant primary adult erythroid cells and suggest potenetial therapy for sickle cell disease (SCD) and severe beta-thalassemias.

  16. Inactivation of HDAC1 or HDAC2 induces gamma-globin expression without altering cell cycle or proliferation.

  17. Findings indicate that both antisickling beta-globin and gamma-globin lentiviral vectors demonstrate efficient gene transfer into sickle cells.

  18. Data indicate that hydroxyurea (HU) induces SAR1 protein expression, which in turn activates gamma-globin expression, predominantly through the Gialpha/JNK/Jun pathway.

  19. There is synergism between developmental stage-specific recruitments of the ATF2 protein complex and expression of gamma-globin during erythropoiesis.

  20. Data suggest that segregation of BCL11A haplotype 2 indicating an involvement of this locus in Hb F expression.

HBG1 Antigen Profile

Antigen Summary

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Gene names and symbols associated with Hemoglobin, gamma A (HBG1) ELISA Kits

  • hemoglobin subunit gamma 1 (Hbg1) antibody
  • hemoglobin subunit gamma 1 (HBG1) antibody
  • hemoglobin subunit gamma 1 L homeolog (hbg1.L) antibody
  • hemoglobin, gamma G (HBG1) antibody
  • hemoglobin subunit gamma-1 (LOC100982657) antibody
  • beta-globin antibody
  • Hbb-y antibody
  • hbb1 antibody
  • Hbe1 antibody
  • HBG1 antibody
  • HBG2 antibody
  • hbga antibody
  • hbgr antibody
  • hsggl1 antibody

Protein level used designations for Hemoglobin, gamma A (HBG1) ELISA Kits

epsilon 3 globin , hemoglobin Y beta-like embryonic chain , hemoglobin Y, beta-like embryonic chain , hemoglobin, epsilon 1 , A-gamma globin , gamma A hemoglobin , gamma globin , gamma-1-globin , hb F Agamma , hemoglobin gamma-1 chain , hemoglobin gamma-a chain , hemoglobin subunit gamma-1 , hemoglobin, gamma, regulator of , beta-1-globin , hemoglobin beta-1 chain , hemoglobin beta-major chain , hemoglobin subunit beta-1 , hemoglobin, gamma G , gamma-2 globin , Hemoglobin subunit gamma-1 , Gamma-1-globin , Hemoglobin gamma-1 chain , Hemoglobin gamma-A chain

94164 Rattus norvegicus
3047 Homo sapiens
734881 Xenopus laevis
736917 Pan troglodytes
100982657 Pan paniscus
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