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IL-37 Proteins

(Interleukin 37 (IL37))
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

14 results

IL37 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Pubmed 1 reference
Catalog No. ABIN1307749
 
IL37 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Catalog No. ABIN5509527
 
IL37 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % (SDS-PAGE) SDS
Catalog No. ABIN5564493
 
IL37 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7454154
 
IL37 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % (SDS-PAGE) SDS
Catalog No. ABIN1344168
 
IL37 Origin: Human Host: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA
Catalog No. ABIN7577670
 
IL37 Origin: Human Host: HEK-293 Cells Recombinant >95 % (SDS-PAGE)
Catalog No. ABIN7566269
 
IL37 Origin: Human Host: Escherichia coli (E. coli) Recombinant >90 % as determined by SDS-PAGE. WB, SDS, Imm, ELISA, AcA Active
Catalog No. ABIN7607748
 
IL37 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1096915
 
IL37 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, Imm, PC
Catalog No. ABIN7398191
 
IL37 Origin: Human Host: HEK-293 Cells Recombinant >95 % (SDS-PAGE)
Catalog No. ABIN7566271
 
IL37 Origin: Human Host: HEK-293 Cells Recombinant >95 % (SDS-PAGE)
Catalog No. ABIN7566270
 
IL37 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2723380
 
IL37 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE. WB
Catalog No. ABIN5608463
 
  • Type Protein
    • Protein
  • Application
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Immunogen (Imm)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Positive Control (PC)
    • Standard (STD)
  • Reactivity
    • Human
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Wheat germ
  • Binding Specificity
    • AA 46-218
    • Monomer
    • AA 1-218
    • AA 27-192
    • AA 2-192
    • AA 53-218
    • Transcript Variant 1
    • partial
  • Conjugate
    • His tag
    • Un-conjugated
    • Fc Tag
    • GST tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
  • Biological Activity
    • Biologically Active
  • Supplier
    • antibodies-online
    • OriGene
    • ProSci

Latest Publications for our IL-37 Proteins

Yang, Fang, Chen, Ma, Xiao, Zou, Zheng, Yan, Liao, Chen, Fang, Yu, Liu, Dong: "Elevated plasma interleukin-37 playing an important role in acute coronary syndrome through suppression of ROCK activation." in: Oncotarget, Vol. 8, Issue 6, pp. 9686-9695, (2018) (PubMed).

Wu, Meng, Ji, Cheng, Yu, Zhao, Tony, Liu, Zhou, Chang, Zhong, Zhu, Zhang, Mao, Zeng: "Interleukin-37 ameliorates myocardial ischaemia/reperfusion injury in mice." in: Clinical and experimental immunology, Vol. 176, Issue 3, pp. 438-51, (2014) (PubMed).

Fujita, Inoue, Seto, Komitsu, Aihara: "Interleukin-37 is elevated in subjects with atopic dermatitis." in: Journal of dermatological science, Vol. 69, Issue 2, pp. 173-5, (2013) (PubMed).

Aliases for IL-37 Proteins

interleukin 37 (IL37) Proteins
FIL1 Proteins
FIL1(ZETA) Proteins
FIL1Z Proteins
IL-1F7 Proteins
IL-1H Proteins
IL-1H4 Proteins
IL-1RP1 Proteins
IL-37 Proteins
IL1F7 Proteins
IL1H4 Proteins
IL1RP1 Proteins
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