Jerky Homolog (Mouse) Proteins (JRK)

JRK is the human homolog of the mouse jerky gene. Additionally we are shipping JRK Antibodies (4) and many more products for this protein.

list all proteins Gene Name GeneID
JRK 8629
JRK 16469
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Top JRK Proteins at

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available

JRK Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Jerky Homolog (Mouse) (JRK) Interaction Partners

Human Jerky Homolog (Mouse) (JRK) interaction partners

  1. JRK (show CLOCK Proteins) expression was aberrantly elevated in 21% of colorectal cancers, 15% of breast and ovarian cancers and was associated with increased expression of beta-catenin (show CTNNB1 Proteins) target genes and increased cell proliferation

  2. in the adult intestine, Ebd (show DEFB1 Proteins) acts independently of Ewg in physiological Wnt (show WNT2 Proteins) signaling, but cooperates with Ewg to induce the hyperactivation of Wnt (show WNT2 Proteins) target gene expression following Apc1 (show SLC25A24 Proteins) loss. These findings have relevance for human tumorigenesis, as Jerky (JRK/JH8), the human Ebd (show DEFB1 Proteins) homolog, promotes Wnt (show WNT2 Proteins) pathway hyperactivation and is overexpressed in colorectal, breast, and ovarian cancers

Mouse (Murine) Jerky Homolog (Mouse) (JRK) interaction partners

  1. Jerky has a role in epilepsy and consists of tandemly arranged helix-turn-helix/homeodomain-like motifs and binds specific sets of mRNAs

  2. JRK protein associates with a specific chromosomal centromeric locus in the cell cycle G(2) phase.

JRK Protein Profile

Protein Summary

This gene is the human homolog of the mouse jerky gene. The encoded protein has similarity to several nuclear regulatory proteins, including centromere protein B, suggesting that it might function as a DNA-binding protein. Insertional inactivation of this gene in transgenic mice resulted in epileptic seizures. Childhood Absence Epilepsy (CAE) has been mapped to the same chromosomal location (8q24.3) as this gene, making this gene a strong candidate for CAE. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Jerky Homolog (Mouse) Proteins (JRK)

  • Jrk helix-turn-helix protein (JRK)
  • jerky (Jrk)
  • JH8 protein

Protein level used designations for Jerky Homolog (Mouse) Proteins (JRK)

jerky protein homolog , jerky protein

8629 Homo sapiens
16469 Mus musculus
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