Laminin, alpha 1 Proteins (LAMA1)

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.. Additionally we are shipping Laminin alpha 1 Antibodies (59) and Laminin alpha 1 Kits (20) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LAMA1 16772 P19137
LAMA1 284217 P25391
LAMA1 316758  
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Top Laminin alpha 1 Proteins at

Showing 5 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 15 to 18 Days
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 11 to 18 Days

LAMA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)


Rat (Rattus)

More Proteins for Laminin, alpha 1 (LAMA1) Interaction Partners

Mouse (Murine) Laminin, alpha 1 (LAMA1) interaction partners

  1. Laminin is instructive and CaMKII (show CAMK2G Proteins) is non-permissive for the formation of complex aggregates of acetylcholine receptors on myotubes in culture.

  2. Laminin regulates PDGFRbeta cell differentiation, fate determination, cell stemness and muscle development via gpihbp1 (show GPIHBP1 Proteins).

  3. while MMP-9 (show MMP9 Proteins) is not essential for hypoxic-induced cerebral angiogenesis, it plays an important role in post-hypoxic vascular pruning by degrading laminin and claudin-5 (show CLDN5 Proteins)

  4. interaction of alpha6beta1 in embryonic stem cells (ECCs) with laminin-1 activates alpha6beta1/CD151 (show CD151 Proteins) signaling which programs ESCs (show NR2E3 Proteins) toward the endothelial cells lineage fate

  5. These findings suggest that LAMA1 plays a critical role in kidney function and kidney aging by regulating the mesangial cell population and mesangial matrix deposition through TGF-beta (show TGFB1 Proteins)/Smad (show SMAD1 Proteins) signaling.

  6. Mutations in Lama1 allow developing retinal vessels to enter the vitreous where they anastomose with vessels of the hyaloid system which persist and expand

  7. Our data show that the absence of Lama1 has an impact on the Bergmann glia scaffold that aberrantly develops.

  8. Laminin alpha1 chain is not responsible for muscle disease in the mdx (show DMD Proteins) mouse model for Duchenne muscular dystrophy (show DMD Proteins)

  9. This first report of viable Lama1 mouse mutants emphasizes the importance of this gene in retinal development, and data suggest that hypomorphic mutations in human LAMA1 could lead to retinal disease.

  10. Exposure of cryptic domains in the alpha 1-chain of laminin-1 by elastase stimulates macrophages urokinase and matrix metalloproteinase-9 (show MMP9 Proteins) expression.

Human Laminin, alpha 1 (LAMA1) interaction partners

  1. We report here a severe defect of neuromuscular transmission in a consanguineous patient with a homozygous variant in the laminin alpha-5 (show LAMA5 Proteins) subunit gene (LAMA5 (show LAMA5 Proteins)). The variant c.8046C>T (p.Arg2659Trp) is rare and has a predicted deleterious effect. The affected individual, who also carries a rare homozygous sequence variant in LAMA1, had muscle weakness, myopia, and facial tics

  2. LAMA1 SNP rs2089760 plays an important role in the development of PM.

  3. LAMA1 deficiency can lead to alteration in cytoskeletal dynamics, which may invariably lead to alteration in dendrite growth and axonal formation. Patient-derived fibroblasts have impaired adhesion, reduced migration, abnormal morphology and increased apoptosis due to impaired activation of Cdc42 (show CDC42 Proteins), a member of the Rho family of GTPases that is involved in cytoskeletal dynamics.

  4. Sixteen novel LAMA1 variants were identified in fourteen families with Poretti-Boltshauser syndrome. The frameshift variant c.[2935delA] recurred in six unrelated families on a shared haplotype, suggesting a founder effect.

  5. Taken together, these findings suggest that miR (show MLXIP Proteins)-202 may function as a novel tumor suppressor in ESCC by repressing cell proliferation and migration, and its biological effects may attribute the inhibition of LAMA1-mediated FAK (show PTK2 Proteins)-PI3K (show PIK3CA Proteins)-Akt (show AKT1 Proteins) signaling.

  6. Our results indicate that invasion of cervical cancer is accomplished by the remodeling of the interstitial stroma, which process includes decrease and partial replacement of fibronectin (show FN1 Proteins) and collagens by a laminin-rich matrix

  7. Novel PMCA3 missense mutation co-occurring with a heterozygous mutation in LAMA1 impaired cellular Ca2+ homeostasis in patients with Cerebellar Ataxia.

  8. Identification of biallelic mutations in LAMA1 as the cause of cerebellar dysplasia with cysts in seven affected individuals.

  9. Studies indicate that progenitor endothelial cells (ECs), endothelial colony-forming cells (ECFCs), deposit collagen IV (show COL4 Proteins), fibronectin (show FN1 Proteins), and laminin.

  10. miR (show MLXIP Proteins)-9 negatively controls lamin A (show LMNA Proteins) and progerin expression in neural cells.

Zebrafish Laminin, alpha 1 (LAMA1) interaction partners

  1. Loss of lama1 leads to divergent effects on focal adhesion assembly in a spatiotemporally-specific manner. Laminin is required for multiple steps of optic cup morphogenesis, including optic stalk constriction, invagination, and formation of a spherical lens. In lama1(UW1) mutants, loss of epithelial polarity and altered adhesion lead to defective tissue architecture and formation of a disorganized retina.

  2. Analysis of zebrafish laminin-alpha 1 mutants reveals multiple functions for laminin-alpha 1 in the outgrowth and guidance of central nervous system axons

  3. Laminin alpha 1 is needed for lens development in zebrafish embryos.

  4. The phenotypic and genetic analyses of a recessive, larval lethal zebrafish mutant, bal(a69), characterized by severe eye defects and shortened body axis, is reported.

  5. two guidance cues, TAG-1 (show CNTN2 Proteins) and laminin-alpha1, influence the behavior of growth cones during axon pathfinding in vivo

  6. tag1 (show CNTN2 Proteins), lama1 and vangl2 (show VANGL2 Proteins) participate in a common mechanism that integrates signaling between the FBMN and its environment to regulate migration.

Rabbit Laminin, alpha 1 (LAMA1) interaction partners

  1. The distribution of laminin and alphaSMA (show ACTA2 Proteins) in the testis and epididymis might point out to their roles in the male reproduction.

Laminin alpha 1 (LAMA1) Protein Profile

Protein Summary

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.

Gene names and symbols associated with Laminin, alpha 1 Proteins (LAMA1)

  • laminin, alpha 1 (Lama1)
  • laminin subunit alpha 1 (LAMA1)
  • laminin subunit alpha 1 (Lama1)
  • laminin, alpha 1 (LAMA1)
  • laminin, alpha 1 (lama1)
  • laminin subunit alpha 1 (lama1)
  • AA408497 protein
  • LAMA protein
  • LAMA1 protein
  • S-LAM-alpha protein

Protein level used designations for Laminin, alpha 1 Proteins (LAMA1)

S-LAM alpha , S-laminin subunit alpha , laminin A chain , laminin subunit alpha-1 , laminin-1 subunit alpha , laminin-3 subunit alpha , laminin-1 , laminin, alpha 1 , bal , bashful , zmp:0000000656 , laminin subunit alpha-1-like

16772 Mus musculus
284217 Homo sapiens
316758 Rattus norvegicus
374016 Gallus gallus
455302 Pan troglodytes
480201 Canis lupus familiaris
506387 Bos taurus
569971 Danio rerio
722472 Macaca mulatta
100059860 Equus caballus
100357482 Oryctolagus cuniculus
100403734 Callithrix jacchus
100465830 Ailuropoda melanoleuca
100563687 Anolis carolinensis
100625589 Sus scrofa
101083299 Felis catus
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