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LRP1B belongs to the low density lipoprotein (LDL) receptor gene family. Additionally we are shipping LRP1B Antibodies (7) and LRP1B Kits (2) and many more products for this protein.
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Data show that overexpression of full-length mouse Lrp1b leads to impaired cellular proliferation, while humsn LRP1B knockdown has the opposite effect.
that LRP1B interacted with DVL2 (show DVL2 Proteins), inhibited the interaction between DVL2 (show DVL2 Proteins) and Axin (show AXIN1 Proteins), and negatively regulated beta-catenin (show CTNNB1 Proteins)/TCF (show HNF4A Proteins) signaling
LRP1B gene is a target for human papillomavirus integrations and chromosome rearrangements in oropharyngeal squamous cell carcinoma.
LRP1B, BRD2 (show BRD2 Proteins) and CACNA1D (show CACNA1D Proteins) are new candidate genes in fetal metabolic programming of newborns exposed to maternal hyperglycemia.
LRP1B presents with frequent molecular alterations for glioblastoma patients; its deletion may impact patient outcome.
Silencing of LRP1B altered the expression of focal adhesion complex-associated proteins, and Cdc42 (show CDC42 Proteins)/RhoA (show RHOA Proteins) activities.
genetic association studies in Danish population: Quantitative metabolic phenotypes in obesity are associated with SNP in various genes: LRP1B (rs2890652) is associated with body mass index and insulin (show INS Proteins) resistance.
LRP1b shows restricted expression in human tissues and binds to several extracellular ligands, including fibrinogen and apoE (show APOE Proteins)--carrying lipoproteins
Epigenomics and microRNAs inactivate LRP1B, a modulator of the extracellular environment of thyroid cancer cells, and it is deleted in neoplasms.
LRP1B was hypermethylated in four gastric cancer cell lines, and low LRP1B mRNA expression was associated with high methylation levels in gastric cancer cell lines.
Data show that overexpression of full-length mouse Lrp1b leads to impaired cellular proliferation, while human LRP1B knockdown has the opposite effect.
C1q-induced LRP1B and GPR6 proteins expressed early in Alzheimer disease mouse models, are essential for the C1q-mediated protection against amyloid-beta neurotoxicity
Results show that in contrast to LRP1 (show LRP1 Proteins), LRP1b-deficient mice develop normally, most likely due to its restricted expression pattern and functional compensation by LRP1 (show LRP1 Proteins) or other receptors.
both halves of the LRP1B cytoplasmic tail contribute to a unique global conformation, which results in less efficient recognition by endocytic adaptors and a slow endocytosis rate.
This study presents the possibility that LRP1B participates in signal transduction which PICK1 (show PICK1 Proteins) may regulate by inhibiting PKCalpha (show PKCa Proteins) phosphorylation of LRP1B.
LRP1B belongs to the low density lipoprotein (LDL) receptor gene family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands (Liu et al., 2001
low density lipoprotein receptor-related protein 1B
, low density lipoprotein-related protein 1B
, low-density lipoprotein receptor-related protein 1B-like
, LRP-deleted in tumors
, low density lipoprotein receptor related protein-deleted in tumor
, low density lipoprotein-related protein 1B (deleted in tumors)
, low-density lipoprotein receptor-related protein 1B
, low-density lipoprotein receptor-related protein-deleted in tumor