GSAP Proteins

(Pigeon Homolog (PION))

Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD\; MIM 104300). Formation of amyloid-beta is catalyzed by gamma-secretase (see PSEN1\; MIM 104311), a protease with numerous substrates. PION, or GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate, the amyloid-beta precursor protein (APP\; MIM 104760) C-terminal fragment (APP-CTF) (He et al., 2010 [PubMed 20811458]).[supplied by OMIM, Nov 2010].

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10 results

GSAP Protein (AA 1-858) (His tag)

custom-made PION Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Gsap Protein, UniprotID Q3TCV3

3 images

Catalog No. ABIN7563663

Details

GSAP Protein (AA 1-854) (His tag)

custom-made PION Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant GSAP Protein, UniprotID A4D1B5

3 images

Catalog No. ABIN7554045

Details

GSAP Protein (His tag)

PION Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, WB, ELISA

Catalog No. ABIN7577300

Details

GSAP Protein (AA 634-846) (His tag)

PION Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC

Catalog No. ABIN7410046

Details

GSAP Protein (AA 646-858) (His tag)

PION Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC

Catalog No. ABIN7423636

Details

GSAP Protein (AA 616-854) (His tag)

PION Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % SDS, WB, Imm, PC

Catalog No. ABIN7405879

Details

GSAP Protein (AA 1-858) (Strep Tag)

custom-made PION Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA

Catalog No. ABIN3134967

Details

GSAP Protein (AA 1-854) (Strep Tag)

custom-made PION Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA

Catalog No. ABIN3092843