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The protein encoded by PLXNB3 is a member of the plexin family. Additionally we are shipping Plexin B3 Antibodies (38) and Plexin B3 Kits (1) and many more products for this protein.
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Data show that Semaphorin 5A (Sema5A (show SEMA5A Proteins)) and plexin-B3 inhibit glioma cell invasion through Rac1 inactivation.
Data represent a novel signaling of semaphorin 5A and plexin B3 in the control of cell motility by indirect inactivation of Rac1 through RhoGDIalpha.
Plexin-B3 is a functional receptor for semaphorin 5A (show SEMA5A Proteins)
Data suggest an involvement of homophilic interaction of B3 in semaphorin-independent signaling mechanisms positively influencing neuronal morphogenesis or function.
plexin B3 may influence cognitive performance, and the development of white matter in vivo in a way similar to its known stimulating effect on neurite outgrowth in vitro
A virtual expression database search and RT-PCR analysis showed co-expression of SEMA5A (show SEMA5A Proteins) and Plexin B3, and the interaction of SEMA5A (show SEMA5A Proteins) with Plexin B3 was confirmed by co-immunoprecipitation studies.
Data suggest that under physiological conditions Plexin-B3 is not essential for the development and function of the central nervous system.
Plexin B3 strongly stimulates neurite outgrowth of primary murine cerebellar neurons.
These results help to better comprehend mechanisms used for plexin B3 transcriptional regulation.
The protein encoded by this gene is a member of the plexin family. It functions as a receptor for semaphorin 5A, and plays a role in axon guidance, invasive growth and cell migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, plexin 6
, protein Plxnb3