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POPDC2 encodes a member of the POP family of proteins which contain three putative transmembrane domains. Additionally we are shipping POPDC2 Antibodies (9) and many more products for this protein.
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recently a novel family of cAMP effector proteins emerged and was termed the Popeye domain containing (POPDC) family, which consists of three members POPDC1, POPDC2 and POPDC3. POPDC proteins are transmembrane proteins, which are abundantly present in striated and smooth muscle cells. POPDC proteins bind cAMP with high affinity comparable to PKA
Sequential binding of MEIS1 and NKX2-5 on the Popdc2 gene demonstrate a mechanism for spatiotemporal regulation of enhancers during cardiogenesis.
Popdc1 and Popdc2 proteins interact with the potassium channel TREK-1, which leads to increased cell surface expression and enhanced current density
Popdc2 is expressed in various muscle and nonmuscle cell types during embryonic development and in postnatal life
The results showed that popdc2 is a gene important for striated muscle differentiation and cardiac morphogenesis. In addition popdc2 is required for the development of the cardiac conduction system.
This gene encodes a member of the POP family of proteins which contain three putative transmembrane domains. This membrane associated protein is predominantly expressed in skeletal and cardiac muscle, and may have an important function in these tissues.
popeye protein 2
, popeye domain-containing protein 2
, popeye 2
, popeye domain containing protein 2