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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints.
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Mammalian Monoclonal KCNB2 Primary Antibody for ISt, IHC - ABIN1304764
Gravagna, Knoeckel, Taylor, Hultgren, Ribera: Localization of Kv2.2 protein in Xenopus laevis embryos and tadpoles. in The Journal of comparative neurology 2008
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Human Polyclonal KCNB2 Primary Antibody for WB - ABIN1881474
Nyholt, LaForge, Kallela, Alakurtti, Anttila, Färkkilä, Hämaläinen, Kaprio, Kaunisto, Heath, Montgomery, Göbel, Todt, Ferrari, Launer, Frants, Terwindt, de Vries, Verschuren, Brand: A high-density association screen of 155 ion transport genes for involvement with common migraine. in Human molecular genetics 2008
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The fractional contribution of Kv2.2-mediated currents relative to IK decreases during the postnatal maturation of dorsal root ganglion neurons.
The protein levels of KV4.3 (show KCND3 Antibodies) and KV2.2 were up-regulated in the hypertrophic smooth muscle cell membrane.
This study demonistrated that the contribution of Kv2.2 potassium channels in regulating neuronal excitability and a specific role in hearing protection after an acoustic insult. Kv2.2 is expressed in two nuclei of the superior olivary complex.
Kv2.2 modulates somatostatin (show SST Antibodies) release in delta-cells.
These data offer Kv2.2 as a molecular target to study the role of the specific subpopulation of basal forebrain GABAergic neurons.
It was concluded that Kv2.2-containing channels have a distinctive initial segment location and crucial function in maintaining AP amplitude by regulating the interspike potential during high frequency firing.
Kv2.1 (show KCNB1 Antibodies), but not Kv2.2 (KCNB2), forms clusters of 6-12 tetrameric channels at the plasma membrane and facilitates insulin (show INS Antibodies) exocytosis
Five de novo mutations were identified in four genes (SCNN1A (show SCNN1A Antibodies), KCNJ16 (show KCNJ16 Antibodies), KCNB2, and KCNT1 (show KCNT1 Antibodies)) in three Brugada syndrome patients
The rs2128158 in KCNB2 showed significant associations with MaxDrinks.
stromatoxin-1 -sensitive KV2 (show KCNA6 Antibodies)-containing channels are expressed in detrusor smooth muscle (DSM); they control DSM excitability, intracellular Ca2 (show CA2 Antibodies)+ levels, and myogenic and nerve-evoked contractions
miR-1 by anti-miR-1 inhibitor oligonucleotides alleviated the downregulation of KCNE1 (show KCNE1 Antibodies) and KCNB2, the shortening of AERP, and the increase in the IKs
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel. The gene is expressed in gastrointestinal smooth muscle cells.
potassium voltage-gated channel, Shab-related subfamily, member 2
, potassium voltage-gated channel subfamily B member 2-like
, potassium voltage-gated channel subfamily B member 2
, voltage-gated potassium channel subunit Kv2.2
, potassium voltage-gated channel, Shab-related subfamily, member 2, potassium channel alpha subunit Kv2.2
, delayed rectifier potassium channel protein
, potassium channel Kv2.2
, voltage-gated potassium channel alpha subunit Kv2.2