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Associates with Polycomb group (PcG) multiprotein complexes\; the complex class is required to maintain the transcriptionally repressive state of some genes (By similarity).. Additionally we are shipping SCMH1 Antibodies (42) and and many more products for this protein.
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Here, we report a microdeletion of 170,6 Kb at Xp22.13 (17.733.948-17.904.576) (GRCh37/hg19).The microdeletion harbors the NHS, SCLML1, and RAI2 (show RAI2 Proteins) genes and results in a phenotype consistent with Nance-Horan syndromesyndrome and developmental delay
the molecular evolutionary pattern of SCML1 in diverse primate species showed a strong signature of adaptive evolution which is caused by Darwinian positive selection
Loss of Scmh1 caused derepression of Hoxb4 (show HOXB4 Proteins) and Hoxa9 (show HOXA9 Proteins), direct targets of Polycomb (show CBX2 Proteins)-group complex 1-mediated transcriptional silencing in hematopoietic cells.
Scmh1 is involved in regulating the sequential changes in chromatin modifications at the XY chromatin domain of the pachytene spermatocytes.
Associates with Polycomb group (PcG) multiprotein complexes\; the complex class is required to maintain the transcriptionally repressive state of some genes (By similarity).
polycomb protein SCMH1
, sex comb on midleg-like protein 1
, sex comb on midleg 1
, sex comb on midleg homolog 1 (Drosophila)
, polycomb protein SCMH1-like
, sex comb on midleg-like 1
, sex comb on midleg-like 3
, sex comb on midleg homolog 1
, Scm polycomb group protein homolog 1