Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein Proteins (SYNCRIP)

SYNCRIP encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. Additionally we are shipping Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein Antibodies (105) and Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SYNCRIP 10492 O60506
SYNCRIP 56403 Q7TMK9
SYNCRIP 363113 Q7TP47
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Top Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,370.21
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,370.21
Details
Escherichia coli (E. coli) Human GST tag Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein (SYNCRIP) (AA 2-191), (partial) protein (GST tag) 1 mg 60 to 71 Days
$1,842.50
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Wheat germ Human GST tag 2 μg 11 to 12 Days
$338.33
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Yeast Rat His tag   1 mg 60 to 71 Days
$3,518.17
Details

SYNCRIP Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein (SYNCRIP) Interaction Partners

Human Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein (SYNCRIP) interaction partners

  1. The EGF/hnRNP Q1-induced translation of Aurora-A mRNA is mediated by the mTOR and ERK pathways.

  2. A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets.

  3. our data indicate that hnRNP Q1 is a novel trans-acting factor that binds to Aurora-A mRNA 5'-UTRs and regulates its translation, which increases cell proliferation and contributes to tumorigenesis in colorectal cancer

  4. SYNCRIP is required for survival of leukemia cells. SYNCRIP controls the myeloid leukemia stem cell program.

  5. The acidic domain is a unique structural feature of the splicing factor SYNCRIP.

  6. hnRNPQ6 is required for APOBEC1-enhanced IL8 production.

  7. The hnRNP Q is a novel substrate of SHP2 and the SHP2 activity may be also involved in RNA metabolisms via dephosphorylation of hnRNP Q.

  8. The inhibitory effect of hnRNP Q on YB-1 mRNA translation can be explained by its ability to pro-mote YB-1 binding to the regulatory element within the YB-1 mRNA 3' UTR.

  9. These data indicate that hnRNP Q can stimulate the protein production of HIV-1 Rev-dependent mRNAs without changing mRNA levels and mRNA export, respectively.

  10. Data demonstrate that expression levels of hnRNP A1, Q, K, R, and U influence HIV-1 production by persistently infected

  11. The overexpression of NSAP1 specifically enhanced HCV IRES-dependent translation, and knockdown of NSAP1 by use of a small interfering RNA specifically inhibited the translation of HCV mRNA.

  12. SYNCRIP is transported within the dendrite as a component of mRNA granules

  13. methylation of hnRNPQ is important for its nuclear localization

  14. Results suggest hnRNPQ interacts via its acidic domain (AcD) with Apobec1 and that this interaction is regulated by AcD phosphorylation.

  15. Data demonstrate that hnRNP Q is a splicing modulator of SMN2, further underscoring the potential of hnRNP Q as a therapeutic target for spinal muscular atrophy.

  16. Results demonstrate that galectin-3 stabilizes hnRNP Q via complex formation, and reduction in the hnRNP Q level leads to slow proliferation and less susceptibility to 5-FU.

  17. SYNCRIP participates in both RNA replication and translation in HCV life cycle.

Mouse (Murine) Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein (SYNCRIP) interaction partners

  1. SYNCRIP (synaptotagmin-binding cytoplasmic RNA-interacting protein; also known as hnRNP-Q or NSAP1) is a component of the hepatocyte exosomal miRNA sorting machinery.

  2. SYNCRIP is required to maintain myeloid leukemia survival.

  3. hnRNP Q binds to mCry1 mRNA via the 5'UTR. Furthermore, hnRNP Q inhibits the translation of mCry1 mRNA, leading to altered rhythmicity in the mCRY1 protein profile.

  4. hnRNP-Q1-mediated repression of Gap-43 mRNA translation provides an additional mechanism for regulating GAP-43 expression and function and may be critical for neuronal development.

  5. SYNCRIP-regulated Nox2 mRNA degradation mediates the hypoinflammatory phase of sepsis.

  6. hnRNP-Q2 plays important roles in the regulation of global translation and miRNA-mediated repression of specific mRNAs.

  7. The changes in cytosolic hnRNP Q levels contribute to cell cycle-dependent translational differences in p53 mRNA.

  8. hnRNP Q1 may participate in localization of mRNAs encoding Cdc42 signaling factors in neurites, and thereby may regulate actin dynamics and control neuronal morphogenesis

  9. results revealed essential role for hnRNP-Q1 in regulating dendritic development and focal adhesions, which are mediated by negatively regulating RhoA protein synthesis and signaling; findings provide insight into regulation of RhoA signaling and mechanisms underlying cellular morphogenesis

  10. The circadian-dependent translation of Per1 mRNA was controlled by an internal ribosomal entry site element in the 5= untranslated region of mPer1 mRNA along with the trans-acting factor mouse heterogeneous nuclear ribonucleoprotein Q.

  11. identification of the tyrosine phosphorylated form

  12. The overexpression of NSAP1 specifically enhanced HCV IRES-dependent translation, and knockdown of NSAP1 by use of a small interfering RNA specifically inhibited the translation of HCV mRNA.

Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein (SYNCRIP) Protein Profile

Protein Summary

This gene encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 20.

Gene names and symbols associated with SYNCRIP

  • synaptotagmin binding cytoplasmic RNA interacting protein (SYNCRIP)
  • synaptotagmin binding, cytoplasmic RNA interacting protein (Syncrip)
  • synaptotagmin binding, cytoplasmic RNA interacting protein (syncrip)
  • synaptotagmin binding cytoplasmic RNA interacting protein S homeolog (syncrip.S)
  • synaptotagmin binding cytoplasmic RNA interacting protein (syncrip)
  • synaptotagmin binding cytoplasmic RNA interacting protein (Syncrip)
  • 2610109K23Rik protein
  • 4632417O19Rik protein
  • gry-rbp protein
  • GRYRBP protein
  • hnRNP-Q protein
  • HNRNPQ protein
  • hnrpq1 protein
  • nsap1 protein
  • Nsap1l protein
  • pp68 protein
  • rp1-3j17.2 protein
  • SYNCRIP protein
  • wu:fe02c03 protein
  • wu:fe47h09 protein

Protein level used designations for SYNCRIP

NS1-associated protein 1 , glycine- and tyrosine-rich RNA-binding protein , heterogeneous nuclear ribonucleoprotein Q , RRM RNA binding protein GRY-RBP , hnRNP Q , hnRNP-Q , synaptotagmin-binding, cytoplasmic RNA-interacting protein , liver regeneration-related protein LRRG077 , synaptotagmin binding, cytoplasmic RNA interacting protein , heterogeneous nuclear ribonucleoprotein Q-like

GENE ID SPECIES
10492 Homo sapiens
56403 Mus musculus
326663 Danio rerio
363113 Rattus norvegicus
421831 Gallus gallus
432011 Xenopus laevis
462866 Pan troglodytes
474986 Canis lupus familiaris
511763 Bos taurus
100144726 Xenopus (Silurana) tropicalis
100358009 Oryctolagus cuniculus
100414011 Callithrix jacchus
100463670 Ailuropoda melanoleuca
100542315 Meleagris gallopavo
100579672 Nomascus leucogenys
100723388 Cavia porcellus
100154370 Sus scrofa
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