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May act as a GTPase-activating protein for Rab family protein(s). Additionally we are shipping TBC1D20 Proteins (4) and many more products for this protein.
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Warburg Micro syndrome is caused by TBC1D20 deficiency.
Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans.
The detailed molecular reaction mechanism of a complex between human Rab and RabGAP at the highest possible spatiotemporal resolution and in atomic detail, is described.
The NS5A interaction with TBC1D20 and Rab1 is essential for the viral life cycle.
These findings add TBC1D20 to the network of host factors regulating HIV replication cycle.
TBC1D20 was found to be the first known GAP for Rab1, which is implicated in the regulation of anterograde traffic between the endoplasmic reticulum and the Golgi complex
TBC1D20 has an essential role in the maturation of autophagosomes.
Disruption of Tbc1d20 in mice results in cataracts and aberrant acrosomal formation.
May act as a GTPase-activating protein for Rab family protein(s).
TBC1 domain family member 20