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THAP10 encodes a member of a family of proteins sharing an N-terminal Thanatos-associated domain. Additionally we are shipping THAP10 Proteins (3) and many more products for this protein.
Showing 10 out of 23 products:
Human Polyclonal THAP10 Primary Antibody for ICC, IF - ABIN4359126
Li, Ning, Shi, Chen, Jiang, Gao, Huang, Jing, Huang, Liu, Hu, Liu, Wang, Nervi, Dai, Zhang, Yu: A novel epigenetic AML1-ETO/THAP10/miR-383 mini-circuitry contributes to t(8;21) leukaemogenesis. in EMBO molecular medicine 2017
Altogether, these results revealed an unexpected and important epigenetic mini-circuit of AML1 (show RUNX1 Antibodies)-ETO (show RUNX1T1 Antibodies)/THAP10/miR (show MLXIP Antibodies)-383 in t(8;21) acute myeloid leukaemia, in which epigenetic suppression of THAP10 predicts a poor clinical outcome and represents a novel therapeutic target.
transcripts of LRRC49/THAP10 bidirectional gene pair are co-regulated by estrogen and that hypermethylation of the bidirectional promoter region simultaneously silences both genes.
This gene encodes a member of a family of proteins sharing an N-terminal Thanatos-associated domain. The Thanatos-associated domain contains a zinc finger signature similar to DNA-binding domains. This gene is part of a bidirectional gene pair on the long arm of chromosome 15 that is regulated by estrogen and may play a role in breast cancer.
THAP domain-containing protein 10