Tu Translation Elongation Factor, Mitochondrial (Tufm) ELISA Kits

Tufm encodes a protein which participates in protein translation in mitochondria.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human Tufm Tufm 7284 P49411
Anti-Mouse Tufm Tufm 233870 Q8BFR5
Anti-Rat Tufm Tufm 293481 P85834
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Top Tu Translation Elongation Factor, Mitochondrial ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.156-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$875.60
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Mouse
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$875.60
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Rat
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$875.60
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Cow
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$1,029.60
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Chicken
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$1,095.60
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Dog
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More ELISA Kits for Tu Translation Elongation Factor, Mitochondrial Interaction Partners

Human Tu Translation Elongation Factor, Mitochondrial (Tufm) interaction partners

  1. study revealed a novel role for TUFM as a host restriction factor that exerts an inhibitory effect on avian-signature PB2627E influenza virus propagation in human cells; found that increased TUFM-dependent autophagy correlates with the inhibitory effect on avian-signature influenza virus replication and may serve as a key intrinsic mechanism to restrict avian influenza virus infection in humans

  2. High expression of TUFM is associated with colorectal cancer.

  3. we identify a novel signaling hub centering on the NLRX1 (show NLRX1 ELISA Kits) TUFM protein complex, promoting autophagic flux. Defects in the expression of either NLRX1 (show NLRX1 ELISA Kits) or TUFM result in compromised autophagy when treated with EGFR (show EGFR ELISA Kits) inhibitors.These findings expand our understanding of the components involved in head and neck squamous cell carcinoma autophagy machinery that responds to EGFR (show EGFR ELISA Kits) inhibitors.

  4. TUFM is a novel regulator of epithelial-mesenchymal transition (EMT (show ITK ELISA Kits)); there may be a molecular link between mitochondrial dysfunction and EMT (show ITK ELISA Kits) induction

  5. NLRX1 (show NLRX1 ELISA Kits) and TUFM work in concert to reduce cytokine response and augment autophagy.

  6. Increased expression of TUFM is a promising new prognostic indicator for colorectal carcinoma.

  7. By recruiting Atg5 (show ATG5 ELISA Kits)-Atg12 (show ATG12 ELISA Kits) and NLRX1 (show NLRX1 ELISA Kits), TUFM serves as a nodal checkpoint of the RIG-I (show DDX58 ELISA Kits)-MAVS (show MAVS ELISA Kits) axis. It acts similarly to NLRX1 (show NLRX1 ELISA Kits) by inhibiting RigI (show DDX58 ELISA Kits)-like-receptor-induced IFN-I but promoting autophagy.

  8. Genetic investigation of patients with defective mitochondrial translation led to the discovery of novel mutations in the mitochondrial elongation factor G1 (EFG1 (show GFM1 ELISA Kits)) in one affected baby and in the mitochondrial elongation factor Tu (show EEF1A1 ELISA Kits) (EFTu) in another one

  9. Myoblasts isolated from the MELAS patients show A3243G mutation in tRNALeu(UUR) produces a severe respiratory chain deficiency and this phenotype can be partially suppressed by overexpression of EFTu and EFG2 (show GFM2 ELISA Kits).

  10. Results suggest that the R336Q mutant mt-EFTu variant fails to bind to aminoacylated mitochondrial tRNAs, thus explaining the observed impairment of mitochondrial translation.

Cow (Bovine) Tu Translation Elongation Factor, Mitochondrial (Tufm) interaction partners

  1. Loss of activity is caused by a significant reduction in the ability of EF-Ts(mt) R325W to bind EF-Tu(mt), leading to a defect in nucleotide exchange.

  2. Recombinant mitochondrial EF-Tu prevents thermal aggregation of proteins and enhances protein refolding in vitro.

  3. The arginine residue at position 335 of bovine mitochondrial elongation factor Tu (EF-Tu (show EEF1A1 ELISA Kits)) plays an important role in the binding and EF-Tu-mediated delivery of mitochondrial aminoacyl-tRNAs to the A-site of the ribosome.

Mouse (Murine) Tu Translation Elongation Factor, Mitochondrial (Tufm) interaction partners

  1. By recruiting Atg5 (show ATG5 ELISA Kits)-Atg12 (show ATG12 ELISA Kits) and NLRX1 (show NLRX1 ELISA Kits), TUFM serves as a nodal checkpoint of the RIG-I (show DDX58 ELISA Kits)-MAVS (show MAVS ELISA Kits) axis. It acts similarly to NLRX1 (show NLRX1 ELISA Kits) by inhibiting RigI (show DDX58 ELISA Kits)-like-receptor-induced IFN-I but promoting autophagy.

Tu Translation Elongation Factor, Mitochondrial (Tufm) Antigen Profile

Antigen Summary

This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17.

Gene names and symbols associated with Tufm

  • Tu translation elongation factor, mitochondrial (TUFM) antibody
  • Tu translation elongation factor, mitochondrial (tufm) antibody
  • Tu translation elongation factor, mitochondrial (Tufm) antibody
  • 2300002G02Rik antibody
  • C76308 antibody
  • C76389 antibody
  • COXPD4 antibody
  • D250 antibody
  • EF-TuMT antibody
  • EFTU antibody
  • fi06f04 antibody
  • P43 antibody
  • TUFM antibody
  • wu:fi06f04 antibody
  • zgc:110766 antibody

Protein level used designations for Tufm

Tu translation elongation factor, mitochondrial , elongation factor Tu, mitochondrial-like , elongation factor Tu, mitochondrial , EF-Tu

GENE ID SPECIES
454018 Pan troglodytes
705462 Macaca mulatta
100455214 Pongo abelii
541378 Danio rerio
7284 Homo sapiens
479796 Canis lupus familiaris
281556 Bos taurus
233870 Mus musculus
293481 Rattus norvegicus
430889 Gallus gallus
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