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WFDC2 Proteins

(WAP Four-Disulfide Core Domain 2 (WFDC2))
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008].

18 results

WFDC2 Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274791
 
WFDC2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Pubmed 1 reference
Catalog No. ABIN1325310
 
WFDC2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Catalog No. ABIN7125722
 
WFDC2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Pubmed 1 reference
Catalog No. ABIN2181198
 
WFDC2 Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
Pubmed 2 references
Catalog No. ABIN1047931
 
WFDC2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7597410
 
WFDC2 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319181
 
WFDC2 Origin: Human Host: Escherichia coli (E. coli) Recombinant WB, ELISA, SDS
Catalog No. ABIN7580274
 
WFDC2 Origin: Human Host: Escherichia coli (E. coli) Recombinant WB, ELISA, SDS
Catalog No. ABIN7580273
 
WFDC2 Origin: Human Host: Human Native Standard grade
Catalog No. ABIN5624015
 
WFDC2 Origin: Human Host: HEK-293 Cells Recombinant > 97 % by SDS-PAGE.
Catalog No. ABIN7536542
 
WFDC2 Origin: Human Host: Mammalian Cells Recombinant WB, ELISA, SDS
Catalog No. ABIN7580275
 
WFDC2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, PC, Imm
Catalog No. ABIN7410622
 
WFDC2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2735564
 
WFDC2 Origin: Human Host: Escherichia coli (E. coli) Recombinant WB, PC
Catalog No. ABIN2750241
 
WFDC2 Origin: Rabbit Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1621589
 
WFDC2 Origin: Pig Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1640689
 
WFDC2 Origin: Dog Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1621599
 
  • Type Protein
    • Protein
  • Application
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Positive Control (PC)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Immunogen (Imm)
    • Standard (STD)
  • Reactivity
    • Human
    • Dog
    • Pig
    • Rabbit
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Yeast
    • Human
    • Human Cells
    • Mammalian Cells
    • Wheat germ
  • Binding Specificity
    • AA 31-124
    • AA 28-124
    • AA 27-123
    • AA 29-123
    • AA 30-124
    • full length
  • Conjugate
    • His tag
    • Fc Tag
    • GST tag
    • Un-conjugated
    • His tag,GST tag
    • His-SUMO Tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
    • Native
  • Format
    • Lyophilized
    • Liquid
  • Supplier
    • antibodies-online
    • CUSABIO
    • ACROBiosystems
    • FabGennix
    • OriGene

Latest Publications for our WFDC2 Proteins

Yang, Lu, Guo, Fellman, Ning, Lu, Menon, Kobayashi, Hanash, Celestino, Skates, Bast: "Human epididymis protein 4 antigen-autoantibody complexes complement cancer antigen 125 for detecting early-stage ovarian cancer." in: Cancer, (2019) (PubMed).

Eaton, Shallcross, Mael, Mears, Minkoff, Scoville, Whelan: "Selection of DNA aptamers for ovarian cancer biomarker HE4 using CE-SELEX and high-throughput sequencing." in: Analytical and bioanalytical chemistry, (2015) (PubMed).

LeBleu, Teng, OConnell, Charytan, Müller, Müller, Sugimoto, Kalluri: "Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis." in: Nature medicine, Vol. 19, Issue 2, pp. 227-31, (2013) (PubMed).

Hellström, Raycraft, Hayden-Ledbetter, Ledbetter, Schummer, McIntosh, Drescher, Urban, Hellström: "The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma." in: Cancer research, Vol. 63, Issue 13, pp. 3695-700, (2003) (PubMed).

Kirchhoff, Habben, Ivell, Krull: "A major human epididymis-specific cDNA encodes a protein with sequence homology to extracellular proteinase inhibitors." in: Biology of reproduction, Vol. 45, Issue 2, pp. 350-7, (1992) (PubMed).

Aliases for WFDC2 Proteins

WAP four-disulfide core domain 2 (WFDC2) Proteins
WAP four-disulfide core domain 2 (wfdc2) Proteins
WAP four-disulfide core domain 2 (Wfdc2) Proteins
1600023A02Rik Proteins
BE-20 Proteins
CE4 Proteins
dJ461P17.6 Proteins
EDDM4 Proteins
HE4 Proteins
re4 Proteins
si:ch211-153a8.3 Proteins
WAP5 Proteins
WFDC2 Proteins
WFDC3 Proteins
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