anti-Zic Family Member 3 (ZIC3) Antibodies

ZIC3 encodes a member of the ZIC family of C2H2-type zinc finger proteins. Additionally we are shipping Zic Family Member 3 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ZIC3 7547 O60481
ZIC3 367944  
ZIC3 22773 Q62521
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Zic Family Member 3 Antibodies at antibodies-online.com

Showing 10 out of 71 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ZIC3 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:12500  Positive Control:  ACHN cell lysate Host:  Mouse  Target Name:  ZIC3  Sample Tissue:  Mouse Brain  Antibody Dilution:  1ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA Immunohistochemistry (5μg/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Dog Goat Un-conjugated ELISA   100 μg Log in to see 6 to 7 Days
$247.24
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB ZIC3 Antibody (Center) (ABIN650719) western blot analysis in CEM cell line lysates (35 µg/lane).This demonstrates the ZIC3 antibody detected the ZIC3 protein (arrow). ZIC3 Antibody (Center) (ABIN650719) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Goat Un-conjugated ELISA, IHC   100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ZIC3 Antibody (N-term) (ABIN389243) in HL60 cell line lysates (35 µg/lane).ZIC3(arrow) was detected using the purified polyclonal antibody (1:60dilution). Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ZIC3 antibody (N-term) (ABIN389243), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Cow Goat Un-conjugated ELISA, IHC, IHC (p) Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$484.00
Details
Human Rabbit Un-conjugated IF, IF/ICC, IHC (p), WB Immunofluorescence staining of ZIC3 in HeLa cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-human ZIC3 polyclonal antibody (1 µg/ml) at 4℃ overnight. Then cells were stained with the Alexa Fluor®594-conjugated Goat Anti-rabbit IgG secondary antibody (red)Positive staining was localized to cytoplasm and nucleus. Immunochemical staining of human ZIC3 in human prostate with rabbit polyclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections). 100 μg Log in to see 20 to 21 Days
$218.90
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details

Top referenced anti-Zic Family Member 3 Antibodies

  1. Human Polyclonal ZIC3 Primary Antibody for IHC (p), ELISA - ABIN4369821 : Bedard, Purnell, Ware: Nuclear import and export signals are essential for proper cellular trafficking and function of ZIC3. in Human molecular genetics 2007 (PubMed)
    Show all 3 Pubmed References

More Antibodies against Zic Family Member 3 Interaction Partners

Human Zic Family Member 3 (ZIC3) interaction partners

  1. current understanding of ZIC3 function and describe the potential role ZIC3 plays in important signalling pathways and their links to heterotaxy.

  2. Six novel pathogenic variants were identified in either male patients with heterotaxy or a female patient with multiple male deaths due to heterotaxy in the family. Truncating variants showed abnormal trafficking of mutated ZIC3 proteins.

  3. Targeted Resequencing of 29 Candidate Genes and Mouse Expression Studies Implicate ZIC3 and FOXF1 (show FOXF1 Antibodies) in Human VATER/VACTERL Association

  4. detected the expression level of miR (show MLXIP Antibodies)-564 and ZIC3 protein in tissue specimens, and found a significant negative correlation between them. Patients with low levels of miR (show MLXIP Antibodies)-564 showed a poorer overall survival

  5. ZIC3 sequencing from unrelated patients with heterotaxy and congenital heart disease identified variants in 5.2% of sporadic male cases some of which were novel. Functional analyses show aberrant cytoplasmic localization.

  6. sumoylation targets human ZIC3 primarily on the consensus lysine residue K248, which is critical for the nuclear retention of ZIC3.

  7. Case Reports: situs inversus totalis and X-linked heterotaxy as a result of novel ZIC3 mutation.

  8. ZIC3 mutations are an important etiology in sporadic and familial heterotaxy.

  9. Mutations in Zinc Finger Protein of the Cerebellum 3 were identified in 4 of the 47 patients (8.5%) with heterotaxy syndrome. Our results expand the mutation spectrum of monogenic heterotaxy syndrome with associated cardiac anomalies.

  10. Data show that transcript, termed Zic3-B, encompasses exons 1, 2, and 4 whereas Zic3-A encompasses exons 1, 2, and 3.

Xenopus laevis Zic Family Member 3 (ZIC3) interaction partners

  1. results demonstrate a functional conservation of Zic3 in left-right patterning and uncover a previously unrecognized role for Zic3 in convergent extension morphogenesis during early vertebrate development

  2. Zic3 can suppress Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling and control development of the notochord and Spemann's organizer.

Mouse (Murine) Zic Family Member 3 (ZIC3) interaction partners

  1. When transduced with Oct4 (show POU5F1 Antibodies), Sox2 (show SOX2 Antibodies), and Klf4 (show KLF4 Antibodies) (OSK) into murine fibroblasts, Zic3 and Esrrb (show ESRRB Antibodies) synergistically enhance the reprogramming efficiency by regulating cellular metabolic pathways.

  2. Targeted Resequencing of 29 Candidate Genes and Mouse Expression Studies Implicate ZIC3 and FOXF1 (show FOXF1 Antibodies) in Human VATER/VACTERL Association

  3. The primary effect of Zic3 in heart development occurs during left-right patterning.

  4. Zic3 is required in the migrating primitive streak for node morphogenesis and left-right patterning

  5. Heterotaxy in patients with premature termination codon-containing ZIC3 transcripts probably arises due to loss of ZIC3 function alone.

  6. These data provide basis for further understanding the molecular mechanisms underlying the complex interaction of Zic3 with signaling pathways involved in the early establishment of laterality.

  7. study demonstrates that Zic3 and Gli3 (show GLI3 Antibodies) expression overlap in developing limbs and that Zic3 converts Gli3 (show GLI3 Antibodies) from repressor to activator in vitro; results indicate two Gli (show GLI1 Antibodies) superfamily members that cause disparate human congenital malformation syndromes interact genetically and demonstrate the importance of Zic3 in regulating Shh (show SHH Antibodies) pathway in developing limbs

  8. Data show that transcript, termed Zic3-B, encompasses exons 1, 2, and 4 whereas Zic3-A encompasses exons 1, 2, and 3.

  9. Data demonstrate an important pathway for regulation of Nanog (show NANOG Antibodies) expression in pluripotent ESCs (show NR2E3 Antibodies) through direct activation by Zic3.

  10. A complex syndrome of left-right axis, central nervous system and axial skeleton defects in Zic3 mutant mice.

Zic Family Member 3 (ZIC3) Antigen Profile

Protein Summary

This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs.

Gene names and symbols associated with ZIC3

  • Zic family member 3 (ZIC3) antibody
  • Zic family member 3 (Zic3) antibody
  • Zic family member 3 S homeolog (zic3.S) antibody
  • zinc finger protein of the cerebellum 3 (Zic3) antibody
  • Bn antibody
  • HTX antibody
  • HTX1 antibody
  • RGD1561261 antibody
  • VACTERLX antibody
  • zic3-A antibody
  • ZNF203 antibody

Protein level used designations for ZIC3

Zic family member 3 (odd-paired homolog, Drosophila) , heterotaxy 1 , zinc finger protein 203 , zinc finger protein ZIC 3 , zinc finger protein of the cerebellum 3 , Zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) , XZic3 , Zic family member 3 (odd-paired homolog) , Zic family member 3 heterotaxy 1 , odd-paired , xlZic3 , zinc finger protein Zic3-A

GENE ID SPECIES
7547 Homo sapiens
367944 Rattus norvegicus
422251 Gallus gallus
492171 Canis lupus familiaris
100156863 Sus scrofa
541035 Bos taurus
394375 Xenopus laevis
22773 Mus musculus
Selected quality suppliers for anti-Zic Family Member 3 (ZIC3) Antibodies
Did you look for something else?