AKT2 Protein (His-GST)
Quick Overview for AKT2 Protein (His-GST) (ABIN7317085)
Target
See all AKT2 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This AKT2 protein is labelled with His-GST.
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Purpose
- Recombinant Human AKT2/PKB beta Protein (His & GST Tag)
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Sequence
- Met 1-Glu481
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Characteristics
- A DNA sequence encoding the human AKT2 (NP_001617.1) (Met1-Glu481) was expressed with a C-terminal polyhistidine-tagged GST tag at the N-terminus (his-GST).
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) protein
AKT2 Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, WB
V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) proteinAKT2 Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, WB
V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) (AA 1-123) protein (His-IF2DI Tag)AKT2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) (Active) protein (Myc-DYKDDDDK Tag)AKT2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, PI, STD Active
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Expiry Date
- 6 months
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- AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))
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Alternative Name
- AKT2/PKB beta
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Background
- HIHGHH,PKBB,PKBBETA,PRKBB,RAC-BETA,AKT2 (AKT Serine/Threonine Kinase 2) is a Protein Coding gene. Diseases associated with AKT2 include Hypoinsulinemic Hypoglycemia With Hemihypertrophy and Diabetes Mellitus, Noninsulin-Dependent. Among its related pathways are Constitutive Signaling by AKT1 E17K in Cancer and RANK Signaling in Osteoclasts. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is AKT1.
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Molecular Weight
- 83.6 kDa
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Gene ID
- 208
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NCBI Accession
- NP_001617
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UniProt
- P31751
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Pathways
- PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, TLR Signaling, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Hepatitis C, VEGF Signaling
Target
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