Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 6 (SLC17A6) (AA 501-582) antibody

Catalog No. ABIN1027711

Product Details

Target: Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 6 (SLC17A6)

Binding Specificity: AA 501-582

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)

Specificity: Detects ~60 kDa.

Cross-Reactivity: Human, Mouse, Rat

Purification: Protein G Purified

Immunogen: Fusion protein amino acids 501-582 (cytoplasmic C-terminus) of rat VGlut2

Clone: S29-29

Isotype: IgG1

Application Details

Application Notes:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Comment:

1 μg/ml of ABIN1027711 was sufficient for detection of VGLut2 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details

Target: Solute Carrier Family 17 (Vesicular Glutamate Transporter), Member 6 (SLC17A6)

Alternative Name: VGLUT2 (SLC17A6 Products)

Synonyms: 2900073D12Rik antibody, DNPI antibody, VGLUT2 antibody, VGluT2 antibody, Dnpi antibody, Vglut2 antibody, VGLUT2.1 antibody, blu antibody, si:packt73.2 antibody, si:packt90.2 antibody, si:xx-packt73.2 antibody, slc17a6 antibody, vglut2a antibody, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 antibody, solute carrier family 17 member 6 antibody, solute carrier family 17 (vesicular glutamate transporter), member 6b antibody, Slc17a6 antibody, SLC17A6 antibody, slc17a6b antibody

Background: The ATP-dependent, chloride-sensitive vesicular glutamate transporters (VGLUT) include BNPI (VGLUT1), VGLUT2 (DNPI) and VGLUT3. The brain expresses BNPI (brain specific Na+-dependent inorganic phosphate (Pi) cotransporter) and VGLUT2 in a complementary fashion. The telencephalic regions express BNPI, whereas the lower brainstem and diencephalic regions express VLGUT2. Rat pinealocytes express both BNPI and VGLUT2. The striatum, hippocampus, cerebral cortex and raphe nuclei express VGLUT3 in a small number of neurons. Pancreatic α and β cells express BNPI and VGLUT2 in response to glucose concentrations. Human VGLUT3 shares a 72 % sequence homology with VLGUT2 and BNPI.

Gene ID: 84487

NCBI Accession: NP_445879

UniProt: Q9JI12