Lamin A/C antibody (R453W)
Quick Overview for Lamin A/C antibody (R453W) (ABIN1042618)
Target
See all Lamin A/C (LMNA) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- R453W
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Specificity
- EDMD-associated lamin A/C mutant R453W
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Purification
- Protein G
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Immunogen
- KLH-coupled peptide from Lamin A/C, human (Immunogen Sequence: 449-GKFVWLRNK-457).
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Isotype
- IgG1
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Application Notes
- Optimal antibody dilution should be determined by titration, however as a guideline try,WB: 1:8,000 (Predicted Mw is 65 kDa)
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Comment
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Myeloma, fusion partners: X63-Ag8.653
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Purified antibody (from supernatant) containing PBS + 0.1 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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: "Monoclonal antibodies specific for disease-associated point-mutants: lamin A/C R453W and R482W." in: PLoS ONE, Vol. 5, Issue 5, pp. e10604, (2010) (PubMed).
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: "Monoclonal antibodies specific for disease-associated point-mutants: lamin A/C R453W and R482W." in: PLoS ONE, Vol. 5, Issue 5, pp. e10604, (2010) (PubMed).
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- Lamin A/C (LMNA)
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Alternative Name
- Lamin A+C R453W
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Background
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Synonyms:
LMNA -
Pathways
- Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
Target
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