SYNE2 antibody (AA 1-459)

Catalog No. ABIN1042628

The Mouse Monoclonal anti-SYNE2 antibody has been validated for WB, IP, IF, ICC and EM. It is suitable to detect SYNE2 in samples from Human. There are 3+ publications available.

Quick Overview for SYNE2 antibody (AA 1-459) (ABIN1042628)

Target: SYNE2 (Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SYNE2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Electron Microscopy (EM)

Clone: K20-478-5

Product Details anti-SYNE2 Antibody

Binding Specificity: AA 1-459

Purification: Protein G purified

Immunogen: Residues 1-459 of human Nesprin-2

Application Details

Application Notes: Optimal antibody dilution should be determined by titration, however as guideline try at 1:2500 for western blot, & 1:500 for IF

Comment:

Myeloma, fusion partners: Pai / BalbC

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified antibody in PBS + 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-SYNE2 antibody (ABIN1042628)

Neumann, Schneider, Daugherty, Gottardi, Eming, Beijer, Noegel, Karakesisoglou: "Nesprin-2 interacts with {alpha}-catenin and regulates Wnt signaling at the nuclear envelope." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34932-8, (2010) (PubMed).

Libotte, Zaim, Abraham, Padmakumar, Schneider, Lu, Munck, Hutchison, Wehnert, Fahrenkrog, Sauder, Aebi, Noegel, Karakesisoglou: "Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope." in: Molecular biology of the cell, Vol. 16, Issue 7, pp. 3411-24, (2005) (PubMed).

Zhen, Libotte, Munck, Noegel, Korenbaum: "NUANCE, a giant protein connecting the nucleus and actin cytoskeleton." in: Journal of cell science, Vol. 115, Issue Pt 15, pp. 3207-22, (2002) (PubMed).

Target Details for SYNE2

Target: SYNE2 (Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2))

Alternative Name: Nesprin 2

Background: Synonyms:
DKFZP434H2235 antibody,DKFZp686E01115 antibody,DKFZp686H1931 antibody,FLJ11014 antibody,FLJ43727 antibody,FLJ45710 antibody,FLJ46790 antibody,KIAA1011 antibody,Nesprin2 antibody,NUA antibody,NUANCE antibody,Nuclear envelope spectrin repeat protein 2 antibody,Nucleus and actin connecting element antibody,Nucleus and actin connecting element protein antibody,Protein NUANCE antibody,Spectrin repeat containing nuclear envelope 2 antibody,Synaptic nuclear envelope protein 2 antibody,Synaptic nuclei expressed gene 2 antibody,SYNE 2 antibody,SYNE2 antibody

Gene ID: 19052

OMIM: 608442

Pathways: Maintenance of Protein Location