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IL-2 antibody (Biotin)

IL2 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1043809
  • Target See all IL-2 (IL2) Antibodies
    IL-2 (IL2) (Interleukin 2 (IL2))
    Reactivity
    • 127
    • 89
    • 42
    • 14
    • 9
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    • 6
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    • 1
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    • 1
    Human
    Host
    • 110
    • 79
    • 59
    • 10
    • 4
    • 2
    • 1
    Rabbit
    Clonality
    • 138
    • 123
    • 1
    Polyclonal
    Conjugate
    • 145
    • 36
    • 23
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    • 14
    • 9
    • 3
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    This IL-2 antibody is conjugated to Biotin
    Application
    • 155
    • 122
    • 69
    • 63
    • 40
    • 28
    • 24
    • 22
    • 14
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    • 8
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    • 4
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    • 2
    • 2
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    • 1
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    Western Blotting (WB), ELISA
    Specificity
    This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. This purified antibody has been heated to 56°C for 30 minutes. In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant human IL-2 in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.
    Characteristics
    IL-2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
    Purification
    purified
    Immunogen
    This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant human IL-2 protein.
    Immunogen Type: RecombinantProtein
    Isotype
    IgG
    Top Product
    Discover our top product IL2 Primary Antibody
  • Application Notes
    This purified antibody has been tested for use in ELISA and western blotting. By western blot a band approximately 15 kDa in size corresponding to human IL-2 protein is expected in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.
    Comment

    Gene Name: IL2

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
    Concentration
    1.1 mg/ml
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store vial at 4° C prior to opening. This product is stable at 4° C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
    Expiry Date
    12 months
  • Bazan: "Unraveling the structure of IL-2." in: Science (New York, N.Y.), Vol. 257, Issue 5068, pp. 410-3, (1992) (PubMed).

  • Target
    IL-2 (IL2) (Interleukin 2 (IL2))
    Alternative Name
    IL-2 (IL2 Products)
    Synonyms
    IL2 antibody, IL-2 antibody, il2 antibody, TCGF antibody, lymphokine antibody, Il-2 antibody, POIL2 antibody, interleukin 2 antibody, interleukin-15 antibody, IL2 antibody, il2 antibody, LOC100303688 antibody, Il2 antibody
    Background
    IL-2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
    Synonyms: Interleukin-2, IL-2, IL2, T-cell growth factor, TCGF, Aldesleukin, Lymphokine
    Gene ID
    3558
    NCBI Accession
    NP_000577
    UniProt
    P60568
    Pathways
    JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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