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PLK1 antibody (AA 331-508)

PLK1 Reactivity: Human, Mouse WB, ELISA, IHC, FACS Host: Mouse Monoclonal 3C11 unconjugated
Catalog No. ABIN1098105
  • Target See all PLK1 Antibodies
    PLK1 (Polo-Like Kinase 1 (PLK1))
    Binding Specificity
    • 26
    • 17
    • 15
    • 12
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 331-508
    Reactivity
    • 132
    • 49
    • 45
    • 8
    • 8
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 111
    • 20
    • 2
    • 1
    Mouse
    Clonality
    • 107
    • 27
    Monoclonal
    Conjugate
    • 80
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PLK1 antibody is un-conjugated
    Application
    • 104
    • 47
    • 30
    • 28
    • 27
    • 20
    • 19
    • 16
    • 9
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human PLK1 (AA: 331-508) expressed in E. coli.
    Clone
    3C11
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Lin, Sun, Wang: "Suppression of Polo like kinase 1 (PLK1) by p21(Waf1) mediates the p53-dependent prevention of caspase-independent mitotic death." in: Cellular signalling, Vol. 23, Issue 11, pp. 1816-23, (2011) (PubMed).

    Yoshioka, Kimura, Saio, Era, Okano: "Plk1 is negatively regulated by RNF8." in: Biochemical and biophysical research communications, Vol. 410, Issue 1, pp. 57-61, (2011) (PubMed).

    Susilowati, Okamura, Hirota, Shono, Yoshida, Murakami, Tabata, Nagamune, Haneji, Miyake: "Intermedilysin induces EGR-1 expression through calcineurin/NFAT pathway in human cholangiocellular carcinoma cells." in: Biochemical and biophysical research communications, Vol. 404, Issue 1, pp. 57-61, (2011) (PubMed).

  • Target
    PLK1 (Polo-Like Kinase 1 (PLK1))
    Alternative Name
    PLK1 (PLK1 Products)
    Synonyms
    PLK antibody, STPK13 antibody, plk antibody, PLK-1 antibody, Plx1 antibody, stpk13 antibody, Plk antibody, cb525 antibody, cb636 antibody, ik:tdsubc_2d1 antibody, wu:fb37g11 antibody, wu:fb76g03 antibody, xx:tdsubc_2d1 antibody, polo like kinase 1 antibody, polo like kinase 1 S homeolog antibody, polo-like kinase 1 antibody, polo-like kinase 1 (Drosophila) antibody, Serine/threonine-protein kinase plk-1 antibody, PLK1 antibody, plk1.S antibody, plk1 antibody, Plk1 antibody, plk-1 antibody
    Background

    Description: Polo-like kinase 1 (Plk1) plays key roles in many aspects of mitosis. Suppression of Plk1 by p21(Waf1) is responsible for p53-dependent protection against adriamycin-induced caspase-independent mitotic death.

    Aliases: PLK,STPK13

    Molecular Weight
    68 kDa
    Gene ID
    5347
    HGNC
    5347
    Pathways
    Cell Division Cycle, M Phase
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