BAX antibody (AA 44-62)

Catalog No. ABIN1100181

This anti-BAX antibody is a Rabbit Polyclonal antibody detecting BAX in WB. Suitable for Human and Monkey.

Quick Overview for BAX antibody (AA 44-62) (ABIN1100181)

Target: BAX (BCL2-Associated X Protein (BAX))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAX antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BAX Antibody

Binding Specificity: AA 44-62

Specificity: Detects an ~22kD protein, corresponding to the apparent molecular mass of Bax on SDS-PAGE immunoblots. Additional bands of 40 and 42kD are present in all of these cell lysates and these bands are not inhibited by the relevant peptide. Species cross-reactivity: Human, rat, mouse, bovine, porcine, rabbit and monkey.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Panda, Cat (89%) Sheep, Elephant, Dog, Bovine, Horse, Pig (84%).

Purification: Immunoaffinity purified

Immunogen: A 19 residue synthetic peptide ELALDPVPQDASTKKLSEC based on the human Bax (residues 44-62), KLH coupled. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%), Panda, Cat (89%), Sheep, Elephant, Dog, Bovine, Horse, Pig (84%).

Type of Immunogen: Synthetic peptide - KLH conjugated

Isotype: IgG

Application Details

Application Notes: Approved: WB (1:250)

Usage: Suitable for use in Western Blot. Western Blot (ECL): 1:250. Positive control: HeLa Cell Lysate.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for BAX

Target: BAX (BCL2-Associated X Protein (BAX))

Alternative Name: BAX

Background: Name/Gene ID: BAX
Family: Apoptosis

Synonyms: BAX, BCL2-associated X protein, Bcl2-L-4, Apoptosis regulator BAX, Bcl-2-like protein 4, BCL2L4

Gene ID: 581

UniProt: Q07812

Pathways: p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response