CHEK2 antibody (AA 2-18)

Catalog No. ABIN1100786

The Rabbit Polyclonal anti-CHEK2 antibody is suitable to detect CHEK2 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for CHEK2 antibody (AA 2-18) (ABIN1100786)

Target: CHEK2 (Checkpoint Kinase 2 (CHEK2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHEK2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHEK2 Antibody

Binding Specificity: AA 2-18

Specificity: Recognizes an epitope atthe N-terminus of Chk2 (Checkpoint Kinase 2). Detects a 60 kD protein. Positive control: Jurkat cell lysate.

Purification: Immunoaffinity purified

Immunogen: Peptide corresponding to aa 2-18 of human Chk2

Isotype: IgG

Application Details

Application Notes: Approved: WB (, 0.5 - 1 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, stable for 1 year. Avoid freeze-thaw cycles.

Target Details for CHEK2

Target: CHEK2 (Checkpoint Kinase 2 (CHEK2))

Alternative Name: CHEK2 / CHK2

Background: Name/Gene ID: CHEK2
Subfamily: CDS1
Family: Protein Kinase

Synonyms: CHEK2, BA444G7, Cds1 homolog, Checkpoint kinase 2, Checkpoint-like protein CHK2, CHK2 checkpoint homolog, CHK2, HCds1, LFS2, RAD53, Rad53 homolog, HCHK2, HuCds1, PP1425

Gene ID: 11200

UniProt: O96017

Pathways: p53 Signaling, Apoptosis, Cell Division Cycle