CACNA1H antibody (N-Term)

Catalog No. ABIN1105622

Product Details anti-CACNA1H Antibody

Target: CACNA1H (Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNA1H antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Reacts with Human 259 kDa CACNA1H protein.

Cross-Reactivity (Details): Species reactivity (expected):Mouse and RatSpecies reactivity (tested):Human.

Purification: Affinity Chromatography on Protein A

Immunogen: Synthetic peptide derived from N-term domain of Human CACNA1H protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in distilled water.

Buffer: 0.1 M Tris, 0.1 M Glycine, 2 % Sucrose, None

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store lyophilized antibody at -20 °C Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CACNA1H

Target: CACNA1H (Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H))

Alternative Name: CACNA1H (CACNA1H Products)

Synonyms: CACNA1HB antibody, Cav3.2 antibody, ECA6 antibody, EIG6 antibody, MNCb-1209 antibody, alpha13.2 antibody, calcium voltage-gated channel subunit alpha1 H antibody, calcium channel, voltage-dependent, T type, alpha 1H subunit antibody, CACNA1H antibody, Cacna1h antibody

Background: Voltage-dependent Ca++ channels mediate Ca++ entry into excitable cells in response to membrane depolarization, and they are involved in a variety of Ca++-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression. Calcium channels are highly diverse, multimeric complexes composed of an α1 subunit, an intracellular β subunit, a disulfide linked α2/δ subunit and a transmembrane γ subunit. Ca++ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types. T-type Ca++ currents are activated and inactivated more rapidly and at more negative membrane potentials than other Ca++ current types. T-type Ca++ channels enhance odor sensitivity by lowering the threshold of spike generation in olfactory receptor cells (ORCs).Synonyms: Cav3.2, Low-voltage-activated calcium channel alpha1 3.2 subunit, Voltage-dependent T-type calcium channel subunit alpha-1H, Voltage-gated calcium channel subunit alpha Cav3.2

Gene ID: 8912

NCBI Accession: NP_001005407

Pathways: C21-Steroid Hormone Metabolic Process