PAX6 antibody (Internal Region)

Catalog No. ABIN1108593

The Rabbit Polyclonal anti-PAX6 antibody (ABIN1108593) specifically detects PAX6 in WB and EIA. The antibody is reactive with Human, Mouse, Rat, Zebrafish (Danio rerio) and Xenopus laevis samples.

Quick Overview for PAX6 antibody (Internal Region) (ABIN1108593)

Target: PAX6 (Paired Box 6 (PAX6))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX6 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-PAX6 Antibody

Binding Specificity: Internal Region

Specificity: Reacts with the Human 95 kDa PAX6 protein. Cross react with Mouse, Rat, Chicken, Zebrafish, Xenopus laevis and other species due to sequence homology.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse, Rat, Xenopus, Zebrafish.

Purification: Affinity Chromatography on Protein A

Immunogen: Synthetic peptide derived from internal part of Human PAX6 protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in distilled water.

Buffer: 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PAX6

Target: PAX6 (Paired Box 6 (PAX6))

Alternative Name: PAX6

Background: PAX6 is a transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. PAX6 is required for the differentiation of pancreatic islet alpha cells and competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. The Pax6-5A isoform appears to function as a molecular switch that specifies target genes.Synonyms: AN2, Aniridia type II protein, Oculorhombin, Paired box protein Pax-6, Pax-6

Gene ID: 5080

NCBI Accession: NP_000271

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis