PAX6 antibody (Internal Region)

Catalog No. ABIN1108593

Product Details anti-PAX6 Antibody

Target: PAX6 (Paired Box 6 (PAX6))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX6 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: Reacts with the Human 95 kDa PAX6 protein. Cross react with Mouse, Rat, Chicken, Zebrafish, Xenopus laevis and other species due to sequence homology.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse, Rat, Xenopus, Zebrafish.

Purification: Affinity Chromatography on Protein A

Immunogen: Synthetic peptide derived from internal part of Human PAX6 protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in distilled water.

Buffer: 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PAX6

Target: PAX6 (Paired Box 6 (PAX6))

Alternative Name: PAX6 (PAX6 Products)

Synonyms: pax6 antibody, an2 antibody, mgda antibody, wagr antibody, pax-6 antibody, pax6a antibody, xpax6 antibody, XLPAX6 antibody, MGC52531 antibody, PAX-6 antibody, AN antibody, AN2 antibody, D11S812E antibody, MGDA antibody, WAGR antibody, Pax-6 antibody, pax6b antibody, 1500038E17Rik antibody, AEY11 antibody, Dey antibody, Gsfaey11 antibody, Sey antibody, PAXZF-A antibody, Pax6.1 antibody, cb280 antibody, fc20e07 antibody, pax-a antibody, pax[zf-a] antibody, paxzfa antibody, wu:fc20e07 antibody, zfpax-6a antibody, zfpax-6b antibody, paired box 6 antibody, paired box 6 L homeolog antibody, paired box 6 S homeolog antibody, paired box 6a antibody, PAX6 antibody, pax6 antibody, Pax6 antibody, pax6.L antibody, pax6.S antibody, pax6a antibody

Background: PAX6 is a transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. PAX6 is required for the differentiation of pancreatic islet alpha cells and competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. The Pax6-5A isoform appears to function as a molecular switch that specifies target genes.Synonyms: AN2, Aniridia type II protein, Oculorhombin, Paired box protein Pax-6, Pax-6

Gene ID: 5080

NCBI Accession: NP_000271

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis