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TRIB3 antibody (N-Term)

TRIB3 Reactivity: Human, Mouse, Rat WB, IHC (fro), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1109329
  • Target See all TRIB3 Antibodies
    TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
    Binding Specificity
    • 16
    • 12
    • 11
    • 8
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 67
    • 27
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 74
    • 5
    Rabbit
    Clonality
    • 75
    • 4
    Polyclonal
    Conjugate
    • 40
    • 7
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRIB3 antibody is un-conjugated
    Application
    • 56
    • 44
    • 14
    • 14
    • 13
    • 13
    • 12
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    Specificity
    Reacts with Human 39 kDa TRIB-3 protein.
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography on Protein A
    Immunogen
    Synthetic peptide derived from N-terminal domain of Human TRIB-3
    Top Product
    Discover our top product TRIB3 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore in distilled water.
    Buffer
    0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None
    Handling Advice
    Avoid repeated freezing and thawing.
  • Target
    TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
    Alternative Name
    TRIB3 (TRIB3 Products)
    Synonyms
    zgc:76966 antibody, TRIB3 antibody, C20orf97 antibody, NIPK antibody, SINK antibody, SKIP3 antibody, TRB3 antibody, Ifld2 antibody, Nipk antibody, TRB-3 antibody, Trb3 antibody, tribbles pseudokinase 3 antibody, trib3 antibody, TRIB3 antibody, Trib3 antibody
    Background
    A novel inhibitor of cell division, Tribbles, blocks mitosis at a critical point in Drosophila morphogenesis. Recently, mammalian homologues of Tribbles (Trbs) have been identified that control mitogen-activated protein kinase (MAPK) activity. TRIB3 also known as TRB-3, SINK, and SKIP3 is a member of Trbs family. Overexpression of this protein inhibits NF-kB-dependent transcription induced by tumor necrosis factor (TNF) stimulation or its downstream signaling proteins but does not inhibit NF-kB translocation to the nucleus and binding to DNA. TRIB3/SKIP3 is also overexpressed in multiple human tumors and is regulated by hypoxia.Synonyms: NIPK, SKIP3, TRB-3, TRB3, Tribbles homolog 3
    Gene ID
    57761
    NCBI Accession
    NP_066981
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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