Tyrosine Hydroxylase antibody

Catalog No. ABIN1109422

This Mouse Monoclonal antibody specifically detects Tyrosine Hydroxylase in WB, IHC (p), IP and IHC (fro). It exhibits reactivity toward Human, Rat, Mouse and Rabbit.

Quick Overview for Tyrosine Hydroxylase antibody (ABIN1109422)

Target: Tyrosine Hydroxylase (TH)

Reactivity: Human, Rat, Mouse, Rabbit

Host: Mouse

Clonality: Monoclonal

Conjugate: This Tyrosine Hydroxylase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: TH-100

Product Details anti-Tyrosine Hydroxylase Antibody

Specificity: This antibody reacts to Tyrosine 3-monooxygenase.

Purification: Goat anti-Mouse IgG Affinity Chromatography

Immunogen: Rat Tyrosine Hydroxylase(TH)

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 1.2 % Sodium Acetate or neutral PBS

Concentration: 0.1 mg/mL

Buffer: 1.2 % Sodium Acetate, with 2 mg BSA and 0.01 mg Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Tyrosine Hydroxylase

Target: Tyrosine Hydroxylase (TH)

Alternative Name: Tyrosine 3-Monooxygenase (TH)

Background: Tyrosine hydroxylase is involved in the conversion of phenylalanine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Human TH gene contains 13 primary exons and spans approximately 8 kb. TH is in the 11p15.5 regionSynonyms: TYH, Tyrosine 3-hydroxylase

Gene ID: 25085

NCBI Accession: NP_036872

UniProt: P04177

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour