Geminin antibody

Catalog No. ABIN1112893

Product Details anti-Geminin Antibody

Target: Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Geminin antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Purification: affinity purified

Isotype: IgG

Application Details

Application Notes: WB (1:500), ICC (1:50). Other applications have not been tested. The optimal dilutions should be determined by end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Expiry Date: 12 months

Target Details for Geminin

Target: Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

Alternative Name: Geminin (GMNN Products)

Synonyms: CG3183 antibody, Dm Geminin antibody, Dm geminin antibody, Dmel\\CG3183 antibody, Gem antibody, Geminin antibody, anon-WO0257455.1 antibody, gem antibody, l(2)k14019 antibody, v(2)k09107 antibody, sb:cb254 antibody, zgc:66217 antibody, GB16871 antibody, GMNN antibody, geminin antibody, dyak_GLEANR_833 antibody, DyakGE24654 antibody, GE24654 antibody, LOC100049517 antibody, AW546347 antibody, geminin, DNA replication inhibitor antibody, CG3183 gene product from transcript CG3183-RA antibody, geminin antibody, GE24654 gene product from transcript GE24654-RA antibody, GMNN antibody, geminin antibody, gmnn antibody, LOC410093 antibody, Dyak\geminin antibody, Gmnn antibody

Background: Geminin, DNA replication inhibitor, also known as GMNN, is a nuclear protein made up of about 200 amino acids, with a molecular weight of approximately 25 kDa, and it is present in most eukaryotics and highly conserved across species. Numerous functions have been elucidated for Geminin including roles in metazoan cell cycle, cellular proliferation, cell lineage commitment, and neural differentiation. It inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC).

Pathways: EGFR Signaling Pathway, DNA Replication