Cardiac Troponin T2 antibody
Quick Overview for Cardiac Troponin T2 antibody (ABIN112502)
Target
See all Cardiac Troponin T2 (cTnT) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- This antibody is specific for Cardiac Troponin T and does not react with the Skeletal form. The epitope has been mapped to a region between amino acids 60-71 of the native protein.
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No Cross-Reactivity
- Fish, Rat (Rattus), Goat, Dog (Canine), Pig (Porcine), Mouse (Murine), Cat (Feline), Rabbit
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Cross-Reactivity (Details)
- Species reactivity (tested):Human, Bovine.
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Purification
- Affinity Chromatography on Protein A
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Immunogen
- Troponin T from Human heart.
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Isotype
- IgG1
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Application Notes
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ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.09 % Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))
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Alternative Name
- Cardiac Troponin T
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Background
- Cardiac Troponin T, a 36 kDa protein, is the tropomyosin binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations within the protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the gene undergo alternative splicing that results in many tissue specific isoforms.Synonyms: TNNT2, TnTc, cTnT
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Gene ID
- 7139
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NCBI Accession
- NP_000355
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UniProt
- P45379
Target
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