APOC3 antibody (Biotin)

Catalog No. ABIN113012

The Goat Polyclonal anti-APOC3 antibody is suitable to detect APOC3 in samples from Human. It has been validated for WB and EIA.

Quick Overview for APOC3 antibody (Biotin) (ABIN113012)

Target: APOC3 (Apolipoprotein C-III (APOC3))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This APOC3 antibody is conjugated to Biotin

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-APOC3 Antibody (Biotin)

Specificity: Binds to Apo CIII. No cross-reaction to Apo AI, Apo AII, Apo B-100, Apo CI, Apo CII and Apo E.

Purification: Human Apo CIII-Sepharose affinity column.

Immunogen: Purified human Apolipoprotein CIII

Application Details

Application Notes: Can be used to detect the existence of Apo CIII in plasma and lipoproteins, forimmunoassay and immunoblotting. Dilution for immunoblot and ELISA range: 8,000 to 30,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Reconstitutein 0.5 mL distilled water.

Concentration: 1.2 mg/mL

Buffer: 10 mM PBS, 0.15 M NaCl, pH 7.2 with 0.02 % sodium azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for APOC3

Target: APOC3 (Apolipoprotein C-III (APOC3))

Alternative Name: Apolipoprotein C III (Apo CIII)

Background: At least 9 distinct polymorphic forms of apolipoproteins are known. The apolipoproteins act as stabilizers of the intact lipoprotein particles. Quantitative measurements of HDL, LDL and VLDL particles in human serum are often used to estimate an individuals' relative risk of coronary heart disease. In addition, quantitative immunological measurements of certain apolipoproteins (especially A1 and B) have been suggested to be more accurate estimators of coronary heart disease than measurements of lipoprotein particles (especially HDL and LDL). Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. It inhibits lipoprotein lipase and hepatic lipase and it is thought to delay catabolism of triglyceride-rich particles. An increase in ap °C-III levels induces the development of hypertriglyceridemia.Synonyms: Apo-CIII, Ap °C-III, Ap °C3, Apolipoprotein C-III, Apolipoprotein C3

Gene ID: 345

NCBI Accession: NP_000031

UniProt: P02656

Pathways: Carbohydrate Homeostasis, Lipid Metabolism