FGF5 antibody
Quick Overview for FGF5 antibody (ABIN115772)
Target
See all FGF5 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Reacts with Human Fibroblast Growth Factor 5 (FGF-5).
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Purification
- Affinity Chromatography on Protein A
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Immunogen
- Recombinant Human FGF-5.
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Isotype
- IgG1
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Application Notes
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Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofHuman FGF-5 (27.6 μg/mL), a concentration of 100 μg/mL. ELISA: This antibody can be used at a concentration of 4.0-8.0 μg/mL, as a Captureantibody in conjunction with a compatible secondary reagent to yield satisfactory resultsin a Sandwich ELISA (using 100 μL/well antibody solution).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore in sterile water to a concentration of 1.0 mg/mL.
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Buffer
- PBS without preservatives
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Preservative
- Without preservative
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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- FGF5 (Fibroblast Growth Factor 5 (FGF5))
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Alternative Name
- FGF5
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Background
- FGF-5 is a secreted heparin binding growth factor belonging to the FGF family. Proteins of this family play a central role in prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-5 binds to FGFR 1c and 2c, and plays a regulatory role in the hair growth cycle.Synonyms: FGF-5, Fibroblast growth factor 5, HBGF5, Heparin-binding growth factor 5, Smag-82
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Gene ID
- 2250
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NCBI Accession
- NP_004455
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UniProt
- P12034
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Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Target
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