Granulin antibody

Catalog No. ABIN1169131

This Rabbit Polyclonal antibody specifically detects Granulin in WB and ELISA. It exhibits reactivity toward Human.It has been mentioned in 1 publication

Quick Overview for Granulin antibody (ABIN1169131)

Target: Granulin (GRN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Granulin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Granulin Antibody

Purpose: anti-Granulin C (human), pAb

Specificity: Recognizes human granulin C. Detects a band of ~12 kDa by Western blot. Cross-reacts with human progranulin.

Cross-Reactivity (Details): Cross-reacts with human progranulin.

Characteristics: Polyclonal Antibody. Recognizes human granulin C. Detects a band of ~12 kDa by Western blot. Cross-reacts with human progranulin. Source: Rabbit. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Granulins have possible cytokine-like activity. They are important in normal development, inflammation, wound repair, and tumorigenesis.

Sterility: 0.2 μm filtered

Immunogen: Recombinant human granulin C.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Preservative: Without preservative

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 6 months after receipt when stored at -20°C.

Expiry Date: 6 months

References for anti-Granulin antibody (ABIN1169131)

Holler, Taylor, Deng, Kukar: "Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by GRN Mutations." in: eNeuro, Vol. 4, Issue 4, (2018) (PubMed).

Target Details for Granulin

Target: Granulin (GRN)

Background:

Alternate Names/Synonyms: Granulin-5, GRN C

Product Description: Granulins have possible cytokine-like activity. They are important in normal development, inflammation, wound repair, and tumorigenesis.

UniProt: P28799