RELM alpha antibody

Catalog No. ABIN1169355

The Rat Monoclonal anti-RELM alpha antibody (Clone MREL 127) (ABIN1169355) specifically detects RELM alpha in WB and ELISA. The antibody is reactive with Mouse samples.

Quick Overview for RELM alpha antibody (ABIN1169355)

Target: RELM alpha

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This RELM alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: MREL 127

Product Details anti-RELM alpha Antibody

Purpose: anti-RELM-alpha (mouse), mAb (MREL 127)

Specificity: Recognizes mouse RELM-alpha. Detects a band of ~10 kDa by Western blot.

Characteristics: Monoclonal Antibody. Recognizes mouse RELM-alpha. Detects a band of ~10 kDa by Western blot. Isotype: Rat IgG2akappa. Clone: MREL 127. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. RELM-alpha is a member to the family of adipocyte-secreted proteins called adipocytokines. It is abundantly expressed in white adipose tissue but not in preadipocytes, nor 3T3-L1 adipocytes. RELM-alpha is involved in the regulation of colonic inflammation and might be a link between colonic injury, glucose tolerance, and energy intake.

Sterility: 0.2 μm filtered

Immunogen: Recombinant mouse RELM-alpha.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Preservative: Without preservative

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for RELM alpha

Target: RELM alpha

Alternative Name: RELM-alpha

Background:

Alternate Names/Synonyms: Resistin-like Molecule-alpha FIZZ1, PMNG1, HIMF

Product Description: RELM-alpha is a member to the family of adipocyte-secreted proteins called adipocytokines. It is abundantly expressed in white adipose tissue but not in preadipocytes, nor 3T3-L1 adipocytes. RELM-alpha is involved in the regulation of colonic inflammation and might be a link between colonic injury, glucose tolerance, and energy intake. Recently, RELM-alpha (from epidermis) has been shown to be induced by skin microbiota. The function of RELM-alpha is to kill bacteria of the skin via membrane disruption. RELM-alpha is induced by vitamin A and explains the mechanism by which vitamin A regulates skin immunity.

UniProt: Q9EP95