RELM alpha antibody

Catalog No. ABIN1169356

This Mouse Monoclonal antibody specifically detects RELM alpha in WB and ELISA. It exhibits reactivity toward Rat.

Quick Overview for RELM alpha antibody (ABIN1169356)

Target: RELM alpha

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This RELM alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: RREL 803

Product Details anti-RELM alpha Antibody

Purpose: anti-RELM-alpha (rat), mAb (RREL 803)

Specificity: Recognizes rat RELM-alpha. Detects a band of ~10.5 kDa by Western blot. Weakly cross-reacts with mouse RELM-alpha.

Cross-Reactivity (Details): Weakly cross-reacts with mouse RELM-alpha.

Characteristics: Monoclonal Antibody. Recognizes rat RELM-alpha. Detects a band of ~10.5 kDa by Western blot. Weakly cross-reacts with mouse RELM-alpha. Isotype: Mouse IgG2akappa. Clone: RREL 803. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. RELM-alpha is a member to the family of adipocyte-secreted proteins called adipocytokines. It is abundantly expressed in white adipose tissue but not in preadipocytes, nor 3T3-L1 adipocytes. RELM-alpha is involved in the regulation of colonic inflammation and might be a link between colonic injury, glucose tolerance, and energy intake.

Sterility: 0.2 μm filtered

Immunogen: Recombinant rat RELM-alpha.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Preservative: Without preservative

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for RELM alpha

Target: RELM alpha

Alternative Name: RELM-alpha

Background:

Alternate Names/Synonyms: Resistin-like Molecule-alpha, FIZZ1, PMNG1, HIMF

Product Description: RELM-alpha is a member to the family of adipocyte-secreted proteins called adipocytokines. It is abundantly expressed in white adipose tissue but not in preadipocytes, nor 3T3-L1 adipocytes. RELM-alpha is involved in the regulation of colonic inflammation and might be a link between colonic injury, glucose tolerance, and energy intake. Recently, RELM-alpha (from epidermis) has been shown to be induced by skin microbiota. The function of RELM-alpha is to kill bacteria of the skin via membrane disruption. RELM-alpha is induced by vitamin A and explains the mechanism by which vitamin A regulates skin immunity.

UniProt: Q99P85