RELM alpha antibody

Catalog No. ABIN636644

There is 1 publication for this product available. The Rabbit Polyclonal anti-RELM alpha antibody is suitable to detect RELM alpha in samples from Mouse. It has been validated for WB, ELISA and InhibAb.

Quick Overview for RELM alpha antibody (ABIN636644)

Target: RELM alpha

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RELM alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (InhibAb)

Product Details anti-RELM alpha Antibody

Purification: Purified

Immunogen: RELM alpha antibody was raised in rabbit using highly pure recombinant murine RELMa as the immunogen.

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

References for anti-RELM alpha antibody (ABIN636644)

Wang, Ismahil, Zhu, Rokosh, Hamid, Zhou, Pogwizd, Prabhu: "CD206+IL-4Rα+ Macrophages Are Drivers of Adverse Cardiac Remodeling in Ischemic Cardiomyopathy." in: Circulation, Vol. 152, Issue 4, pp. 257-273, (2025) (PubMed).

Target Details for RELM alpha

Target: RELM alpha

Background: RELM-alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family, Resistin, RELM-alpha and RELM-beta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELM-alpha and Resistin are secreted exclusively by adipocytes while RELM-beta is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELM-alpha re still unknown.

Molecular Weight: 10.0 kDa (predicted detection band MW)