ITGA4 antibody (FITC)

Catalog No. ABIN118708

This Mouse Monoclonal antibody specifically detects ITGA4 in FACS. It exhibits reactivity toward Human.It has been mentioned in 1 publication

Quick Overview for ITGA4 antibody (FITC) (ABIN118708)

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGA4 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: 44H6

Product Details anti-ITGA4 Antibody (FITC)

Specificity: This antibody recognizes CD49d. Clone 44H6 is reported to induce homoptic aggregation (see Ref.2).

Purification: Protein G affinity Chromatography.

Immunogen: HOON pre-B leukaemia cell line

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: Use 10 μL of neat antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.2, with 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-ITGA4 antibody (FITC) (ABIN118708)

Yang, Hao, Hu: "MicroRNA expression profiles in human adipose-derived stem cells during chondrogenic differentiation." in: International journal of molecular medicine, Vol. 35, Issue 3, pp. 579-86, (2015) (PubMed).

Target Details for ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Alternative Name: CD49d / ITGA4

Background: CD49d, also known as integrin alpha 4 subunit, associates with either integrin beta 1 (to form VLA-4) or beta 7. CD49d is expressed by lymphocytes, monocytes, eosinophils and thymocytes. VLA-4 mediates cell adhesion to VCAM-1 and fibronectin.Synonyms: CD49 antigen-like family member D, Integrin alpha-4, Integrin alpha-IV, VLA-4, VLA4

Gene ID: 3676

NCBI Accession: NP_000876

UniProt: P13612

Pathways: Integrin Complex