ITGA4 antibody (C-Term)

Catalog No. ABIN3043255

Product Details anti-ITGA4 Antibody

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Binding Specificity: AA 999-1028, C-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Integrin alpha-4(ITGA4) detection. Tested with WB, IHC-P in Human,Rat.

Sequence: MWKAGFFKRQ YKSILQEENR RDSWSYINS

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Integrin alpha-4(ITGA4) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
Protein Name: Integrin alpha-4

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Integrin alpha 4 (999-1028aa MWKAGFFKRQYKSILQEENRRDSWSYINS K), different from the related mouse sequence by one amino acid.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Alternative Name: ITGA4 (ITGA4 Products)

Synonyms: CD49D antibody, IA4 antibody, LOC100219853 antibody, integrin subunit alpha 4 antibody, integrin alpha 4 antibody, integrin subunit alpha 4 S homeolog antibody, ITGA4 antibody, Itga4 antibody, itga4.S antibody

Background: ITGA4/Integrin alpha4 is an integrin alpha subunit. It makes up half of the α4β1 lymphocyte homing receptor. The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain. ITGA4 is also mapped to 2q31-q32 by fluorescence in situ hybridization.

Synonyms: 269C wild type antibody|Alpha 4 subunit of VLA 4 receptor antibody|Antigen CD49D antibody| Antigen CD49D, alpha 4 subunit of VLA 4 receptor antibody|CD 49d antibody|CD49 antigen like family member D antibody|CD49 antigen-like family member D antibody|CD49d antibody|CD49d antigen antibody|CDw49d antibody|IA4 antibody|Integrin alpha 4 antibody|Integrin alpha 4 subunit antibody|Integrin alpha IV antibody|Integrin alpha-4 antibody|Integrin alpha-IV antibody|Integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA 4 receptor) antibody| ITA4_HUMAN antibody|ITGA 4 antibody|ITGA4 antibody|LPAM23 antibody|MGC90518 antibody|OTTHUMP00000205320 antibody| Very Late Activation Antigen 4 antibody|Very Late Activation Protein 4 Receptor Alpha 4 Subunit antibody|Very late activation protein 4 receptor, alpha 4 subunit antibody|VLA 4 antibody|VLA 4 subunit alpha antibody|VLA-4 subunit alpha antibody|VLA4 antibody

Gene ID: 3676

UniProt: P13612

Pathways: Integrin Complex