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ITGA4 antibody (Integrin alpha 4) (AA 999-1028) Primary Antibody

ITGA4 Reactivity: Human, Rat IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3043255
$280.00
Plus shipping costs $45.00
100 μg
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Delivery in 4 to 6 Business Days
  • Target
    ITGA4
    Binding Specificity
    • 16
    • 10
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 999-1028, C-Term
    Reactivity
    • 163
    • 138
    • 43
    • 19
    • 11
    • 9
    • 9
    • 8
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 87
    • 84
    • 67
    • 1
    • 1
    Rabbit
    Clonality
    • 161
    • 79
    • 1
    Polyclonal
    Conjugate
    • 106
    • 28
    • 25
    • 20
    • 9
    • 9
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITGA4 antibody is un-conjugated
    Application
    • 166
    • 53
    • 51
    • 47
    • 39
    • 25
    • 23
    • 13
    • 12
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Purpose
    Rabbit IgG polyclonal antibody for Integrin alpha-4(ITGA4) detection. Tested with WB, IHC-P in Human,Rat.
    Sequence
    MWKAGFFKRQ YKSILQEENR RDSWSYINS
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Integrin alpha-4(ITGA4) detection. Tested with WB, IHC-P in Human,Rat.
    Gene Name: integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
    Protein Name: Integrin alpha-4
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human Integrin alpha 4 (999-1028aa MWKAGFFKRQYKSILQEENRRDSWSYINS K), different from the related mouse sequence by one amino acid.
    Isotype
    IgG
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    ITGA4
    Alternative Name
    ITGA4 (ITGA4 Antibody Abstract)
    Synonyms
    CD49D, IA4, LOC100219853, integrin subunit alpha 4, integrin alpha 4, integrin subunit alpha 4 S homeolog, ITGA4, Itga4, itga4.S
    Background
    ITGA4/Integrin alpha4 is an integrin alpha subunit. It makes up half of the α4β1 lymphocyte homing receptor. The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain. ITGA4 is also mapped to 2q31-q32 by fluorescence in situ hybridization.

    Synonyms: 269C wild type antibody|Alpha 4 subunit of VLA 4 receptor antibody|Antigen CD49D antibody| Antigen CD49D, alpha 4 subunit of VLA 4 receptor antibody|CD 49d antibody|CD49 antigen like family member D antibody|CD49 antigen-like family member D antibody|CD49d antibody|CD49d antigen antibody|CDw49d antibody|IA4 antibody|Integrin alpha 4 antibody|Integrin alpha 4 subunit antibody|Integrin alpha IV antibody|Integrin alpha-4 antibody|Integrin alpha-IV antibody|Integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA 4 receptor) antibody| ITA4_HUMAN antibody|ITGA 4 antibody|ITGA4 antibody|LPAM23 antibody|MGC90518 antibody|OTTHUMP00000205320 antibody| Very Late Activation Antigen 4 antibody|Very Late Activation Protein 4 Receptor Alpha 4 Subunit antibody|Very late activation protein 4 receptor, alpha 4 subunit antibody|VLA 4 antibody|VLA 4 subunit alpha antibody|VLA-4 subunit alpha antibody|VLA4 antibody
    Gene ID
    3676
    UniProt
    P13612
    Pathways
    Integrin Complex
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