CDKN2D antibody

Catalog No. ABIN119188

This Mouse Monoclonal antibody specifically detects CDKN2D in WB, IP and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for CDKN2D antibody (ABIN119188)

Target: CDKN2D (Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDKN2D antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: DCS-100-1

Product Details anti-CDKN2D Antibody

Specificity: This antibody recognises p19ink4d, a 19 kDa tumour suppressor protein which is a specific inhibitor of cdk4/cdk6. Clone DCS100.1 co-precipitates cdk4/cdk6 in immunoprecipitation studies.

Purification: Affinity chromatography on Protein G

Immunogen: Full length recombinant p19-His tagged

Isotype: IgG1

Application Details

Application Notes: Western Blot. Immunoprecipitation. Immunohistochemistry on frozen sections. Recommended Positive Control: Spleen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL IgG

Buffer: PBS containing 0.08 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CDKN2D

Target: CDKN2D (Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D))

Alternative Name: CDKN2D / p19INK4d

Background: P19ink4d is periodically expressed during the cell cycle. Maximum induction of p19ink4d occurs as cells enter S phase.Synonyms: Cyclin-dependent kinase 4 inhibitor D, INK4D, p19, p19-INK4d

Gene ID: 1032

NCBI Accession: NP_001791

UniProt: P55273

Pathways: Cell Division Cycle, Sensory Perception of Sound, Mitotic G1-G1/S Phases, Negative Regulation of intrinsic apoptotic Signaling