IDO1 antibody

Catalog No. ABIN121713

The Sheep Polyclonal anti-IDO1 antibody (ABIN121713) specifically detects IDO1 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for IDO1 antibody (ABIN121713)

Target: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This IDO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IDO1 Antibody

Purification: Ammonium Sulphate Precipitation

Immunogen: Recombinant human indoleamine 2,3-dioxygenase

Application Details

Application Notes: Western Blot: 1/1000. Immunohistochemistry on paraffin sections: Sodium citrate buffer pH 6.0 is recommended for this purpose. Does not work on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 27.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for IDO1

Target: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Alternative Name: IDO1 / INDO

Background: IDO is expressed by a wide variety of tissues and IDO can be upregulated by interferon gamma. IDO modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. Reports suggest that IDO is involved in the suppression of the immune response to tumours and blocking the IDO pathway may be a potential target for immunotherapy.Synonyms: 3-dioxygenase, 3-dioxygenase 1, EC=1.13.11.52, IDO, IDO1, INDO, Indoleamine 2, Indoleamine-pyrrole 2

Pathways: Activated T Cell Proliferation