MAP2K2 antibody (Mitogen-Activated Protein Kinase Kinase 2)

Details for Product anti-MAP2K2 Antibody No. ABIN126838, Supplier: Log in to see
Antigen
  • Prkmk2
  • CFC4
  • MAPKK2
  • MEK2
  • MKK2
  • PRKMK2
  • AA589381
  • MK2
  • ATMKK2
  • F27B13.50
  • F27B13_50
  • MAP KINASE KINASE 1
  • MAP kinase kinase 2
  • MK1
  • mitogen activated protein kinase kinase 2
  • mitogen-activated protein kinase kinase 2
  • MAP kinase kinase 2
  • Map2k2
  • MAP2K2
  • MKK2
Alternatives
anti-Human MAP2K2 antibody for Western Blotting
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
357
175
138
12
12
4
3
2
1
1
Host
Mouse
249
99
13
1
Clonality (Clone)
Monoclonal ()
Conjugate
This MAP2K2 antibody is un-conjugated
19
18
15
7
7
7
5
5
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
315
123
119
53
48
41
27
19
15
14
13
11
3
1
Options
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Immunogen Synthetic peptide conjugated to KLH
Clone 8-00E-008
Isotype IgG1
Specificity This antibody specifically recognizes the N-terminus of MEK2 at 45 kDa.
Characteristics Synonyms: MAP kinase kinase 2, ERK activator kinase 2, MAPK/ERK kinase 2, MEK2, MKK2, MAPkinase kinase 2, Dual specificity mitogen-activated protein kinase kinase 2
Purification Size exclusion chromatography
Components incl. positive Control
Plasmids, Primers & others Plasmids, Primers & others MAP2K2 products on genomics-online (e.g. as negative or positive controls)
Antigen Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2)
Alternative Name MAPKK 2 (MAP2K2 Antibody Abstract)
Background MEK (MAP Kinase Kinase) phosphorylates the MAP Kinase on both threonine and tyrosine residues of the activation motif TEY. MEK1 and MEK2 are activated by phosphorylation of two serine residues (Ser 218/222 in MEK1 and Ser 222/226 in MEK2). These phosphorylation sites are substrates of the Raf family of kinases.Synonyms: Dual specificity mitogen-activated protein kinase kinase 2, ERK activator kinase 2, MAP kinase kinase 2, MAPK/ERK kinase 2, MEK2, MKK2
Gene ID 5605
UniProt P36507
Pathways MAPK Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor
Application Notes Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. Positive Control: Cell lysate from untreated HepG2 cells. ELISA: 0.1 μg/mL (protein ELISA).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Reconstitution Restore with 1 mL H2O (15 min, RT)
Buffer 1 mLPBS / 0.09 % Na-azide / PEG and Sucrose
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C/-80 °C
Storage Comment Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) antibody (ABIN126838) anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) antibody
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