CCR1 antibody

Catalog No. ABIN127096

This Rabbit Polyclonal antibody specifically detects CCR1 in WB. It exhibits reactivity toward Human.

Quick Overview for CCR1 antibody (ABIN127096)

Target: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCR1 Antibody

Specificity: The anti-CCR1 antibody recognizes 42 kDa CCR1 in Western blot analysis.

Purification: Protein G purified

Immunogen: Recombinant human CCR1

Application Details

Application Notes: Western Blot: 1-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for CCR1

Target: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Alternative Name: CD191 / CCR1

Background: Chemokines play an important role in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1), eotaxin, as well as several other related chemokines. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation.Synonyms: C-C CKR-1, C-C chemokine receptor type 1, CC-CKR-1, CCR-1, CMKBR1, CMKR1, HM145, LD78 receptor, MIP1 alpha Receptor, Macrophage inflammatory protein 1-alpha receptor, RANTES-R, SCYAR1

Gene ID: 1230

NCBI Accession: NP_001286

UniProt: P32246