Oct-2 antibody (C-Term)

Catalog No. ABIN127201

Product Details anti-Oct-2 Antibody

Target: Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Oct-2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: The antibody recognizes ~52 kDa Oct-2.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide mapping to the c-terminus of human Oct-2

Application Details

Application Notes: Western Blot: 1-4 μg/mL. Immunoprecipitation: 10-20 mg/mL. Immunohistochemistry: 15-25 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, 0.02 % Thimerosal, 30 % Glycerol, 0.5 % BSA

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for Oct-2

Target: Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))

Alternative Name: POU2F2 / OCT2 (POU2F2 Products)

Synonyms: OCT2 antibody, OTF2 antibody, Oct-2 antibody, Pou2f2 antibody, Oct2a antibody, Oct2b antibody, Otf-2 antibody, Otf2 antibody, 2-Oct antibody, Oct2 antibody, POU class 2 homeobox 2 antibody, POU domain, class 2, transcription factor 2 antibody, solute carrier family 22 (organic cation transporter), member 2 antibody, POU2F2 antibody, Pou2f2 antibody, SLC22A2 antibody

Background: Members of Oct family of transcription factors specifically interact with Octamer motif ATGCAAAT, a regulatory element important for tissue- and cell-specific transcription as well as for transcription of a number of housekeeping genes. All of the members of the Oct family contain two highly conserved domains which are separated by 14-26 variable amino acids. These include the POU homeodomain and the POU-specific domain. Both are required for DNA binding and are involved in protein-protein interactions. Evidences indicate that regulation of Oct family transcription factors occurs at the level of phosphorylation.Synonyms: Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, OTF2, Oct-2, Octamer-binding protein 2, Octamer-binding transcription factor 2, Otf-2, POU domain class 2 transcription factor 2

Gene ID: 5452

NCBI Accession: NP_001193954

UniProt: P09086