JAG2 antibody (AA 111-128)

Catalog No. ABIN129632

Supplier Product No.: 600-401-852

Product Details anti-JAG2 Antibody

Target: JAG2 (Jagged 2 (JAG2))

Binding Specificity: AA 111-128

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAG2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Supplier Product No.: 600-401-852

Supplier: Rockland

Purpose: Jagged 2 Antibody

Characteristics: Synonyms: rabbit anti-Jagged-2 antibody, Protein Jagged-2, Jagged2, Jagged 2, Jag2, Jag-2, Jag 2, SER2, HJ2

Purification: Anti-Jagged-2 Antibody produced repeated immunizations with a synthetic peptide corresponding to residues near the middle of the mouse Jagged 2 protein and purified by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.

Sterility: Sterile filtered

Immunogen:

Immunogen: Anti-Jagged-2 [RABBIT) Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 111-128 of Mouse Jagged-2.  Jagged 2 is a Notch ligand, which shows distinct expression patterns in the developing and adult brain that overlaps that of Notch1.  Swiss Prot accession Q9QYE5. Expected to cross-react with rat Jagged-2.

Immunogen Type: Conjugated Peptide

Isotype: IgG

Application Details

Application Notes:

Application Note: Anti-Jagged-2 Antibody has been tested for use in ELISA against the immunizing peptide.  Reactivity in other immunoassays including western blot, immunohistochemistry, and immunofluorescence is expected.

Western Blot Dilution: 1:500- 1:2,000

ELISA Dilution: 1:10,000 - 1:50,000

Other: User Optimized

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for JAG2

Target: JAG2 (Jagged 2 (JAG2))

Alternative Name: Jag2 (JAG2 Products)

Background: Background: Jagged 2 antibody detect the Jagged protein. Jagged 2 is a Notch ligand, which shows distinct expression patterns in the developing and adult brain that overlaps that of Notch1. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. Anti-Jagged 2 antibody is ideal for investigators involved in developmental biology research.

Gene ID: 3714

UniProt: Q9QYE5

Pathways: Notch Signaling, Sensory Perception of Sound