Swi6 (AA 314-328) antibody

Catalog No. ABIN129643

Product Details

Target: Swi6

Binding Specificity: AA 314-328

Reactivity: Schizosaccharomyces pombe

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: This anti-Swi6 Antibody was prepared from whole rabbit antiserum produced by repeated immunizations with a synthetic peptide corresponding aa 314-328 of S.pombe Swi6 protein.

Isotype: IgG

Application Details

Application Notes: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 37 kDa in size corresponding to Swi6 protein by western blotting in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details

Target: Swi6

Synonyms: SPAC824.10c antibody, chromodomain protein Swi6 antibody, swi6 antibody

Background: Swi6 is also known as chromatin-associated swi6 protein and repression of silent mating type loci protein.  This protein recognizes and binds to histone H3 tails that are methylated at Lys-9, leading to epigenetic repression. Swi6 is also involved in the repression of the silent mating-type loci MAT2 and MAT3 and it may be resposible for the compaction of MAT2/3 into a heterochromatin-like conformation which represses the transcription of these silent cassettes. Swi6 also interacts with the cohesin subunit psc3. Swi6 has a nuclear localization and contains 2 chromo domains.
Synonyms: Chromatin-associated protein swi6 swi6 ORF Names: SPAC664.01c, SPAC824.10c

Gene ID: 2541633, 19114361

UniProt: P40381