MHC Class II I-A antibody

Catalog No. ABIN133747

Product Details anti-MHC Class II I-A Antibody

Target: MHC Class II I-A

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This MHC Class II I-A antibody is un-conjugated

Application: Flow Cytometry (FACS)

Specificity: Mouse I-A (Ia.m8)

Purification: Purified from ascitic material via affinity chromatography

Immunogen: C3H.SW spleen . Fusion Partner: SP2/0Ag.14 . Donor: BALB/c

Isotype: IgM

Application Details

Application Notes: This antibody is suitable for use in flow cytometry and can be used to quantitate or eliminate cells bearing the I-A antigen from the appropriate strains of mice.

Restrictions: For Research Use only

Handling

Concentration: 1.0mg/ml

Buffer: Purified Ig buffered in PBS and 0.02% NaN3. (Purified from ascitic material via affinity chromatography)

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for MHC Class II I-A

Target: MHC Class II I-A

Alternative Name: I-A (MHC Class II I-A Products)

Background: Anti- I-A monoclonal antibody reacts with the I-A encoded MHC class II antigen expressed on mouse strains of the H-2 haplotype. It also reacts with the I-A encoded MHC class II antigen expressed on mouse strains of the H- haplotype. The reaction pattern of this antibody with a panel of inbred and recombinant haplotypes demonstrates that the antibody detects the public Ia.m8 determinant. Class II antigens are most highly expressed on antigen-presenting cells including B cells, macrophages, dendritic cells and certain epithelial cells. This antibody is suitable for use in flow cytometry and can be used to quantitate or eliminate cells bearing the I-A antigen from the appropriate strains of mice.